Epidemiological and clinical patterns of 92 patients co-infected with HIV and Mycobacterium leprae from Rio de Janeiro State, Brazil

dc.creatorMenezes, Vinicius M.
dc.creatorNery, José Augusto C.
dc.creatorSales, Anna M.
dc.creatorMiranda, Alice
dc.creatorGalhardo, Maria Clara G.
dc.creatorBastos, Francisco Inácio Pinkusfeld Monteiro
dc.creatorSarno, Euzenir N.
dc.creatorHacker, Mariana A.
dc.date2014-12-10T11:49:59Z
dc.date2015-01-05T15:49:40Z
dc.date2014-12-10T11:49:59Z
dc.date2015-01-05T15:49:40Z
dc.date2014
dc.date.accessioned2023-09-26T20:54:46Z
dc.date.available2023-09-26T20:54:46Z
dc.identifierMENEZES, V. M. et al. Epidemiological and clinical patterns of 92 patients co-infected with hiv and mycobacterium leprae from Rio de Janeiro State, Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene, v.108, n.2, p. 63-70,2014.
dc.identifier00359203
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/9297
dc.identifierDOI:10.1093/trstmh/trt113
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8866045
dc.descriptionBackground: Many articles have shown that HIV infection can modify the clinical course of leprosy, but very scant epidemiological and clinical data about this co-infection are available in the peer-reviewed literature. Methods: We herein describe the geographical distribution and demographic characteristics of 92 HIV/Mycobacterium leprae co-infected patients assisted in a Brazilian Leprosy referral center. A multivariate analysis was performed in order to establish clinical factors associated with type 1 reaction. Results: Co-infected patient admissions have steadily increased over the last years at this referral center. Most patients were men, with a mean age of 32.3 years and presenting with the paucibacillary form of leprosy. The use of antiretroviral therapy (ART) was the only factor associated with type 1 reaction. Most patients were living in the metropolitan area and the north sub area of Rio de Janeiro City. Conclusion: Co-infected patients receiving ART have a greater chance to develop type 1 reaction. Patients living with both HIV and leprosy are likely to live in regions characterized by a high density impoverished population.
dc.formatapplication/pdf
dc.languageeng
dc.rightsopen access
dc.subjectBrazil
dc.subjectLeprosy and HIV co-infection
dc.subjectSocial geography of leprosy
dc.subjectType 1 reaction
dc.titleEpidemiological and clinical patterns of 92 patients co-infected with HIV and Mycobacterium leprae from Rio de Janeiro State, Brazil
dc.typeArticle


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