Potential overestimation of HIV-1 sub-subtype F1 circulation in Rio de Janeiro, Brazil

dc.creatorMarques, Bianca Cristina Leires
dc.creatorMorgado, Mariza Gonçalves
dc.creatorGuimarães, Monick Lindenmeyer
dc.date2018-07-10T15:13:11Z
dc.date2018-07-10T15:13:11Z
dc.date2018
dc.date.accessioned2023-09-26T20:53:12Z
dc.date.available2023-09-26T20:53:12Z
dc.identifierMARQUES, Bianca Cristina Leires; MORGADO, Mariza Gonçalves; GUIMARÂES, Monick Lindenmeyer. Potential overestimation of HIV-1 sub-subtype F1 circulation in Rio de Janeiro, Brazil. Mem Inst Oswaldo Cruz, v.113, n.8, e170483, 6p, 2018.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/27401
dc.identifier10.1590/0074-02760170483
dc.identifier1678-8060
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8865611
dc.descriptionIn Brazil, detection of the HIV-1 sub-subtype F1 has decreased with a simultaneous increase in detection of the recombinant FB and FC forms. In previous HIV-1 env molecular epidemiology studies in Rio de Janeiro, 11.4% of the detected sequences were of the F1 sub-subtype. With the goal of re-estimating the prevalence of the HIV-1 F1 sub-subtype, we performed extended analyses of these samples by examining five genomic regions, resulting in 3.3% being confirmed as F1. Moreover, genomic analysis of 11 of the 21 samples identified as F1 confirmed that nine were F1 and two were BF1. Considering the number of samples assayed, the prevalence of F1 was quite low, which supports the use of different genomic regions for the assessment of HIV-1 classification in countries where several subtypes and recombinant forms co-circulate.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.rightsopen access
dc.subjectHIV-1
dc.subjectEpidemiologia Molecular
dc.subjectTécnicas de Genotipagem
dc.subjectsub-subtipo F1
dc.subjectgenoma completo
dc.subjectRio de Janeiro
dc.subjectHIV-1
dc.subjectsub-subtype F1
dc.subjectfull-length genome
dc.subjectmolecular epidemiology
dc.subjectgenotyping
dc.subjectBrazil
dc.titlePotential overestimation of HIV-1 sub-subtype F1 circulation in Rio de Janeiro, Brazil
dc.typeArticle


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