Twenty years of hantavirus pulmonary syndrome in Brazil: a review of epidemiological and clinical aspects

dc.creatorPinto Junior, Vitor Laerte
dc.creatorHamidad, Amani Moura
dc.creatorAlbuquerque Filho, Dalcy de Oliveira
dc.creatorSantos, Vitorino Modesto dos
dc.date2020-07-21T12:55:14Z
dc.date2020-07-21T12:55:14Z
dc.date2014
dc.date.accessioned2023-09-26T20:53:07Z
dc.date.available2023-09-26T20:53:07Z
dc.identifierPINTO JUNIOR, Vitor Laerte et al. Twenty years of hantavirus pulmonary syndrome in Brazil: a review of epidemiological and clinical aspects. The Journal of Infection in Developing Countries, [s.l.], v. 8, n. 2, p. 137-142, feb. 2014.
dc.identifier1972-2680
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/42319
dc.identifier10.3855/jidc.3254
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8865580
dc.descriptionA JIDC é uma publicação on-line independente com um conselho editorial internacional
dc.descriptionHantavirus infection is transmitted to humans by wild rodents and the most common clinical form in Brazil is the Hantavirus Pulmonary Syndrome (HPS). The first serological evidence of the disease was identified in 1990, in Recife, Pernambuco State, and later in 1993 in Juquitiba, State of São Paulo. Since then there has been a progressive increase in case notification in all regions of the country. The clinical aspects of the disease in Brazil are characterized by a prodromal phase, with nonspecific signs and symptoms of an acute febrile illness. After about three days, respiratory distress develops, accompanied by dry cough that turns progressively productive, evolving to dyspnea and respiratory failure with cardiogenic shock. Although the majority of patients receive hospital care in intensive care therapy units, case-fatality rate in Brazil ranges from 33% to 100% depending on the region. Besides it has to be added the problem of differential diagnosis with other prevalent diseases in the country, like dengue and leptospirosis. Questions about the impact of uncontrolled urbanization and other environmental changes caused by human action have been raised. Due to increasing incidence and high case-fatality, there is an urge to respond to such questions to recommend preventative measures. This article aims to review the main acquisitions in clinical and epidemiological knowledge about HPS in Brazil in the last twenty years.
dc.formatapplication/pdf
dc.languageeng
dc.rightsopen access
dc.subjectDiagnosis, Differential
dc.subjectHantavirus Pulmonary Syndrome
dc.subjectPrevalence
dc.subjectRodentia
dc.subjectHantavirus
dc.subjectBrazil
dc.subjectHantavirus infection
dc.subjectHantavirus pulmonary syndrome
dc.subjectEpidemiology
dc.subjectBrazil
dc.subjectEpidemiologia
dc.subjectSíndrome Pulmonar por Hantavirus
dc.subjectHantavirus
dc.subjectDiagnóstico Diferencial
dc.subjectRoedores
dc.titleTwenty years of hantavirus pulmonary syndrome in Brazil: a review of epidemiological and clinical aspects
dc.typeArticle


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