Leishmania infantum infecting the carnivore Nasua nasua from urban forest fragments in an endemic area of visceral leishmaniasis in Brazilian Midwest

dc.creatorMacedo, Gabriel Carvalho de
dc.creatorBarreto, Wanessa Teixeira Gomes
dc.creatorOliveira, Carina Elisei de
dc.creatorSantos, Filipe Martins
dc.creatorPorfírio, Grasiela Edith de Oliveira
dc.creatorXavier, Samanta Cristina das Chagas
dc.creatorAlves, Fernanda Moreira
dc.creatorSilva, Alanderson Rodrigues da
dc.creatorAndrade, Gisele Braziliano de
dc.creatorRucco, Andreza Castro
dc.creatorAssis, William Oliveira de
dc.creatorJansen, Ana Maria
dc.creatorRoque, André Luiz Rodrigues
dc.creatorHerrera, Heitor Miraglia
dc.date2023-03-31T20:31:00Z
dc.date2023-03-31T20:31:00Z
dc.date2023
dc.date.accessioned2023-09-26T20:52:58Z
dc.date.available2023-09-26T20:52:58Z
dc.identifierMACEDO, Gabriel Carvalho et al. Leishmania infantum infecting the carnivore Nasua nasua from urban forest fragments in an endemic area of visceral leishmaniasis in Brazilian Midwest. Frontiers in Cellular and Infection Microbiology, 12. 1050339, p. 1 - 12, Jan. 2023.
dc.identifier2235-2988
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/57647
dc.identifier10.3389/fcimb.2022.1050339
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8865539
dc.descriptionIntroduction: The aim of the present study was to investigate the occurrence of Leishmania infantum in South American coatis inhabiting two forest fragments in Campo Grande, Mato Grosso do Sul, Midwest region of Brazil, an endemic area of human and canine visceral leishmaniasis (VL). Material and methods: A total of 110 South American coatis were sampled in the conservation unit “Parque Estadual do Prosa” (PEP) and in the residential area “Vila da Base Aérea” (VBA) from March 2018 to April 2019. As a longitudinal study that include up to six recaptures of the same individual, a total of 190 capture events were obtained. Blood, bone marrow and skin samples were obtained for parasitological (axenic culture), serological (Enzyme Linked Immunosorbent Assay – ELISA and Dual-path Platform immunoassay – DPP® CVL) and molecular diagnostic assays (targeting kDNA for Leishmania spp. and L. infantum; and HSP70 followed by sequence analysis). Results: Seropositivity for L. infantum was found in 33 individuals, six in PEP and 27 in VBA. Furthermore, L. infantum was detected by molecular analysis in 16 individuals, seven from PEP and nine from VBA. We also isolated L. infantum from bone marrow of one individual and detected a single positive skin sample in molecular assay from other individual, both from VBA.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFrontiers Media
dc.rightsopen access
dc.subjectInfecção por Leishmania infantum
dc.subjectCarnívoro Nasua nasua
dc.subjectFragmentos florestais urbanos
dc.subjectÀrea endêmica de leishmaniose visceral
dc.subjectCentro-Oeste brasileiro
dc.subjectEndemic area of visceral leishmaniasis
dc.subjectLeishmania infantum infecting
dc.subjectCarnivore Nasua nasua
dc.subjectUrban forest fragments
dc.subjectBrazilian Midwestern
dc.subjectEndemic area
dc.subjectVisceral leishmaniasis
dc.titleLeishmania infantum infecting the carnivore Nasua nasua from urban forest fragments in an endemic area of visceral leishmaniasis in Brazilian Midwest
dc.typeArticle


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