Brasil | Article

Inhibitory effects of d-mannose on trypanosomatid lysis induced by Serratia marcescens

dc.creatorCastro, Daniele P.
dc.creatorMoraes, Caroline S.
dc.creatorGarcia, Eloi S.
dc.creatorAzambuja, Patricia
dc.date2019-10-10T16:24:16Z
dc.date2019-10-10T16:24:16Z
dc.date2007
dc.date.accessioned2023-09-26T20:51:12Z
dc.date.available2023-09-26T20:51:12Z
dc.identifierCASTRO, Daniele P. et al. Inhibitory effects of D-mannose on trypanosomatid lysis induced by Serratia marcescens. Experimental Parasitology, v. 115, p. 200–204, Sept. 2006.
dc.identifier0014-4894
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/36348
dc.identifier10.1016/j.exppara.2006.08.001
dc.identifier1090-2449
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8865047
dc.descriptionStudies were carried out on the effects of different carbohydrates on the lysis of Trypanosoma cruzi, Trypanosoma rangeli and erythocytes caused by the bacteria Serratia marcescens variants SM 365 and RPH. High concentrations of d-mannose were found to protect T. cruzi and T. rangeli markedly diminishing the lysis caused by S. marcescens. However, this carbohydrate is unable to interfere with the hemolysis induced by SM 365 and RPH variants. These results showed that the trypanolytic effect induced by S. marcescens SM 365 and RPH variants is dependent on d-mannose and distinct from the hemolytic activity, strongly suggesting that bacterial fimbriae are relevant to S. marcescens in lysis of parasites.
dc.description2022-01-01
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsrestricted access
dc.subjectManose
dc.subjectSerratia marcescens
dc.subjectTrypanosoma cruzi
dc.subjectTrypanosoma rangeli
dc.subjectHemólise
dc.subjectD-mannose
dc.subjectTrypanosoma cruzi
dc.subjectHemolysis
dc.subjectSerratia marcescens
dc.subjectTrypanosoma rangeli
dc.titleInhibitory effects of d-mannose on trypanosomatid lysis induced by Serratia marcescens
dc.typeArticle


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