HIV aspartyl peptidase inhibitors interfere with cellular proliferation, ultrastructure and macrophage infection of Leishmania amazonensis

dc.creatorSantos, Lívia O.
dc.creatorMarinho, Fernanda A.
dc.creatorAltoé, Ellen F.
dc.creatorVitório, Bianca S.
dc.creatorAlves, Carlos R.
dc.creatorBritto, Constança
dc.creatorMotta, Maria Cristina M.
dc.creatorBranquinha, Marta H.
dc.creatorSantos, André L. S.
dc.creatord`Avila-Levy, Claudia M.
dc.date2019-01-08T13:51:34Z
dc.date2019-01-08T13:51:34Z
dc.date2009
dc.date.accessioned2023-09-26T20:50:39Z
dc.date.available2023-09-26T20:50:39Z
dc.identifierSANTOS, Lívia O. et al. HIV Aspartyl Peptidase Inhibitors Interfere with Cellular Proliferation, Ultrastructure and Macrophage Infection of Leishmania amazonensis. Plos One, v.4, n.3, e4918, 11p, Mar. 2009.
dc.identifier1932-6203
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/30917
dc.identifier10.1371/journal.pone.0004918
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8864878
dc.descriptionLeishmania is the etiologic agent of leishmanisais, a protozoan disease whose pathogenic events are not well understood. Current therapy is suboptimal due to toxicity of the available therapeutic agents and the emergence of drug resistance. Compounding these problems is the increase in the number of cases of Leishmania-HIV coinfection, due to the overlap between the AIDS epidemic and leishmaniasis.
dc.formatapplication/pdf
dc.languageeng
dc.publisherBioMed Central
dc.rightsopen access
dc.subjectLeishmania amazonensis
dc.subjectInibidores da Aspartilpeptidase do HIV
dc.subjectProliferação celular
dc.subjectUltraestrutura
dc.subjectinfecção por macrófagos
dc.subjectLeishmania amazonensis
dc.subjectHIV Aspartyl Peptidase Inhibitors
dc.subjectUltrastructure
dc.subjectCellular Proliferation
dc.subjectMacrophage Infection
dc.titleHIV aspartyl peptidase inhibitors interfere with cellular proliferation, ultrastructure and macrophage infection of Leishmania amazonensis
dc.typeArticle


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