Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine

dc.creatorConceição, Maria José
dc.creatorArgento, Carlos Alberto
dc.creatorCorrêa, Acyr
dc.date2020-10-19T18:19:08Z
dc.date2020-10-19T18:19:08Z
dc.date2000
dc.date.accessioned2023-09-26T20:48:38Z
dc.date.available2023-09-26T20:48:38Z
dc.identifierCONCEIÇÃO, Maria José; ARGENTO, Carlos Alberto; CORRÊA, Acyr. Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 95, n. 3, p. 375-380, May/June 2000.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/44064
dc.identifier10.1590/S0074-02762000000300013
dc.identifier1678-8060
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8864292
dc.descriptionAfter three successive treatments with oxamniquine the continuing elimination of Schistosoma mansoni eggs was observed in patients, who came from various regions of Brazil, with different clinical forms of schistosomiasis. The objective of the present study was to determine the experimental behaviour of five different S. mansoni isolates in Swiss Webster mice that were submitted to treatment with the same drug. The experimental group with failure of treatment showed higher mean number of surviving male worms when it was compared to the group without failure of treatment. These date suggest the possibility of resistance to oxamniquine.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.rightsopen access
dc.subjectSchistosoma mansoni
dc.subjectPacientes
dc.subjectOxamniquine
dc.subjectFailure of treatment
dc.subjectSchistosoma mansoni
dc.subjectPatients
dc.subjectOxamniquine
dc.subjectFailure of treatment
dc.titleStudy of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine
dc.typeArticle


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