Possible mechanisms of Pseudomonas aeruginosa-associated lung disease

dc.creatorAlbuquerque, Cassiano Felipe Gonçalves de
dc.creatorSilva, Adriana Ribeiro
dc.creatorBurth, Patrícia
dc.creatorRocco, Rieken Macêdo
dc.creatorFaria, Mauro Velho Castro
dc.creatorFaria Neto, Hugo Caire Castro
dc.date2016-06-21T13:51:23Z
dc.date2016-07-07T11:59:07Z
dc.date2016-06-21T13:51:23Z
dc.date2016-07-07T11:59:07Z
dc.date2016
dc.date.accessioned2023-09-26T20:48:24Z
dc.date.available2023-09-26T20:48:24Z
dc.identifierALBUQUERQUE, Cassiano Felippe Gonçalves de; et al. Possible mechanisms of Pseudomonas aeruginosa-associated lung disease. International Journal of Medical Microbiology, v.306, n.1, p.20-28, Jan. 2016.
dc.identifier1438-4221
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/14641
dc.identifier10.1016/j.ijmm.2015.11.001
dc.identifier1618-0607
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8864226
dc.descriptionPseudomonas aeruginosa is an opportunistic bacterium causing lung injury in immunocompromised patients correlated with high morbidity and mortality. Many bacteria, including P. aeruginosa, use extracellular signals to synchronize group behaviors, a process known as quorum sensing (QS). In the P. aeruginosa complex QS system controls expression of over 300 genes, including many involved in host colonization and disease. P. aeruginosa infection elicits a complex immune response due to a large number of immunogenic factors present in the bacteria or released during infection. Here, we focused on the mechanisms by which P. aeruginosa triggers lung injury and inflammation, debating the possible ways that P. aeruginosa evades the host immune system, which leads to immune suppression and resistance.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsrestricted access
dc.subjectPseudomonas aeruginosa
dc.subjectLung injury
dc.subjectInflammation
dc.subjectPseudomonas aeruginosa
dc.subjectLesão Pulmonar
dc.subjectInflamação
dc.titlePossible mechanisms of Pseudomonas aeruginosa-associated lung disease
dc.typeArticle


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