Whole cells in enantioselective reduction of benzyl acetoacetate

dc.creatorRibeiro, Joyce Benzaquem
dc.creatorRamos, Aline de Souza
dc.creatorLopes, Raquel de Oliveira Silva
dc.creatorSilva, Gabriela Veloso Vieira da
dc.creatorSouza, Rodrigo Octavio Mendonça Alves de
dc.date2021-05-31T19:51:44Z
dc.date2021-05-31T19:51:44Z
dc.date2014
dc.date.accessioned2023-09-26T20:47:52Z
dc.date.available2023-09-26T20:47:52Z
dc.identifierRIBEIRO, Joyce Benzaquem et al. Whole cells in enantioselective reduction of benzyl acetoacetate. Brazilian Journal of Microbiology, v. 45, n. 3, p. 929-932, Sept. 2014.
dc.identifier1678-4405
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/47469
dc.identifier10.1590/S1517-83822014000300023
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8864077
dc.descriptionThe β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium alginate spheres, K.marxianus showed to be more stable after 2 cycles of reaction.
dc.formatapplication/pdf
dc.languagepor
dc.rightsopen access
dc.subjectBiotransformation
dc.subjectChiral Reduction
dc.subjectβ-Ketoester
dc.subjectKluyveromyces Marxianus
dc.subjectImmobilization
dc.titleWhole cells in enantioselective reduction of benzyl acetoacetate
dc.typeArticle


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