Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides

dc.creatorAmorim, Gustavo Moreira
dc.creatorCorbellini, João Paulo Niemeyer
dc.creatorQuintella, Danielle Carvalho
dc.creatorCuzzi, Tullia
dc.creatorRamos-e-Silva, Márcia
dc.date2019-02-08T13:02:03Z
dc.date2019-02-08T13:02:03Z
dc.date2018
dc.date.accessioned2023-09-26T20:47:02Z
dc.date.available2023-09-26T20:47:02Z
dc.identifierAMORIM, Gustavo Moreira et al. Evaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides. Anais Brasileiros de Dermatologia, v. 93, n. 5, p. 680-685, 2018.
dc.identifier0365-0596
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/31493
dc.identifier10.1590/abd1806-4841.20187134
dc.identifier1806-4841
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8863813
dc.descriptionBackground: Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma. TNMB system is the staging method used in MF, and it not only guides therapeutic management, but represents the main prognostic factor. In order to improve the prognostic evaluation, the Cutaneous Lymphoma International Prognostic Index (CLIPi) was proposed. Objective: To evaluate the performance of CLIPi score for prognostic analysis in patients with early stage MF. Methods: This is a retrospective cross-sectional observational study, with exploratory analysis. The outcome variables were disease progression and related death. Results: One hundred and two patients were stratified according to CLIPi score, being the majority classified as low risk. Patients with intermediate or high risk presented disease progression more frequently than those with low risk (PR: 1.2 / p =0.004 / 95%CI: 1.0 – 1.6). The same did not occur with the variable related death. In addition, survival rates were not consistent with risk stratification. Study Limitations: Small sample and its retrospective analysis. Conclusions: Since CLIPi score was proposed, four other studies that we could consult showed conflicting results, similar to the present study. Further studies are necessary for a recommendation of its use.
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedade Brasileira de Dermatologia
dc.rightsopen access
dc.subjectLymphoma
dc.subjectCutaneous lymphoma
dc.subjectT-cell
dc.subjectMycosis fungoides
dc.titleEvaluation of the cutaneous lymphoma international prognostic index in patients with early stage mycosis fungoides
dc.typeArticle


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