Phenotypic plasticity in adult worms of Schistosoma mansoni (Trematoda:Schistosomatidae) evidenced by brightfield and confocal laser scanning microscopies

dc.creatorNeves, Renata Heisler
dc.creatorSilva, Michele Costa
dc.creatorMartinez, Elaine Machado
dc.creatorBranquinho, Thiago B.
dc.creatorOliveira, Regina Maria Figueiredo de
dc.creatorLenzi, Henrique Leonel
dc.creatorGomes, Delir Corrêa
dc.creatorSilva, José Roberto Machado e
dc.date2012-05-21T16:56:21Z
dc.date2012-05-21T16:56:21Z
dc.date2004
dc.date.accessioned2023-09-26T20:46:37Z
dc.date.available2023-09-26T20:46:37Z
dc.identifierNeves, Renata Heisler et al. Phenotypic plasticity in adult worms of Schistosoma mansoni (Trematoda:Schistosomatidae) evidenced by brightfield and confocal laser scanning microscopies. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 99, n. 2, p. 131-136, mar. 2004.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/4089
dc.identifier10.1590/S0074-02762004000200003
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8863678
dc.descriptionACKNOWLEDGEMENTS To Departamento de Malacologia, Instituto Oswaldo Cruz for providing populations of S. mansoni. To Roberto Magalhães Pinto for critical comments on the manuscript.
dc.descriptionA comparative morphometric study was performed to identify host-induced morphological alterations in Schistosoma mansoni adult worms. A wild parasite population was obtained from a naturally infected rodent (Nectomys squamipes)and then recovered from laboratory infected C3H/He mice. Furthermore, allopatric worm populations maintained for long-term under laboratory conditions in Swiss Webster mice were passed on to N. squamipes. Suckers and genital system (testicular lobes, uterine egg, and egg spine) were analyzed by a digital system for image analysis. Confocal laser scanning microscopy (CLSM) showed details of the genital system (testicular lobes, vitelline glands, and ovary) and the tegument just below the ventral sucker. Significant morphological changes (p < 0.05) were detected in male worms in all experimental conditions, with no significant variability as assessed by CLSM. Significant changes (p < 0.05) were evident in females from the wild population related to their ovaries and vitelline glands, whereas allopatric females presented differences only in this last character. We conclude that S. mansoni worms present the phenotypic plasticity induced by modifications in the parasite's microenvironment, mainly during the first passage under laboratory conditions.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.rightsopen access
dc.subjectSchistosoma mansoni
dc.subjectphenotypic plasticity
dc.subjectAdult worms
dc.subjectNectomys squamipes
dc.subjectC3H/He mice
dc.subjectconfocal laser scanning microscopy
dc.subjectSchistosoma mansoni, anatomia & histologia
dc.subjectMicroscopia Confocal
dc.subjectFenótipo
dc.titlePhenotypic plasticity in adult worms of Schistosoma mansoni (Trematoda:Schistosomatidae) evidenced by brightfield and confocal laser scanning microscopies
dc.typeArticle


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