BuT2 is a member of the third major group of hAT transposons and is involved in horizontal transfer events in the genus Drosophila

dc.creatorRossato, Dirleane Ottonelli
dc.creatorLudwig, Adriana
dc.creatorDeprá, Maríndia
dc.creatorLoreto, Elgion L. S.
dc.creatorRuiz, Alfredo
dc.creatorValente, Vera L. S.
dc.date2018-09-13T19:44:42Z
dc.date2018-09-13T19:44:42Z
dc.date2014
dc.date.accessioned2023-09-26T20:44:59Z
dc.date.available2023-09-26T20:44:59Z
dc.identifierROSSATO, Dirleane Ottonelli et al. BuT2 Is a member of the third major group of hAT transposons and is involved in horizontal transfer events in the Genus Drosophila. Genome Biol. Evol., v. 6 , n. 2, p. 352–365, 2014.
dc.identifier1759-6653
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/28778
dc.identifier10.1093/gbe/evu017
dc.identifier1759-6653
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8863184
dc.descriptionThe hAT superfamily comprises a large and diverse array of DNA transposons found in all supergroups of eukaryotes. Here we characterized the Drosophila buzzatii BuT2 element and found that it harbors a five-exon gene encoding a 643-aa putatively functional transposase. A phylogeny built with 85 hAT transposases yielded, in addition to the two major groups already described, Ac and Buster, a third one comprising 20 sequences that includes BuT2, Tip100, hAT-4_BM, and RP-hAT1. This third group is here named Tip. In addition, we studied the phylogenetic distribution and evolution of BuT2 by in silico searches and molecular approaches. Our data revealed BuT2 was, most often, vertically transmitted during the evolution of genus Drosophila being lost independently in several species. Nevertheless, we propose the occurrence of three horizontal transfer events to explain its distribution and conservation among species. Another aspect of BuT2 evolution and life cycle is the presence of short related sequences, which contain similar 5' and 3' regions, including the terminal inverted repeats. These sequences that can be considered as miniature inverted repeat transposable elements probably originated by internal deletion of complete copies and show evidences of recent mobilization.
dc.formatapplication/pdf
dc.languagepor
dc.publisherOxford University Press
dc.rightsopen access
dc.subjectDrosophila
dc.subjecthAT
dc.subjectDNA Transposable Elements
dc.subjectMites
dc.subjectTransposasas
dc.subjectElementos Transponibles de ADN
dc.subjectTransposases
dc.subjectElementos de DNA Transponíveis
dc.subjectÁcaros
dc.titleBuT2 is a member of the third major group of hAT transposons and is involved in horizontal transfer events in the genus Drosophila
dc.typeArticle


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