qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients

dc.creatorAraujo, Sergio
dc.creatorGoulart, Luiz Ricardo
dc.creatorTruman, Richard W.
dc.creatorGoulart, Isabela Maria B.
dc.creatorVissa, Varalakshmi
dc.creatorLi, Wei
dc.creatorMatsuoka, Masanori
dc.creatorSuffys, Philip
dc.creatorFontes, Amanda B.
dc.creatorRosa, Patricia S.
dc.creatorScollard, David M.
dc.creatorWilliams, Diana L.
dc.date2018-02-27T15:53:58Z
dc.date2018-02-27T15:53:58Z
dc.date2017
dc.date.accessioned2023-09-26T20:44:44Z
dc.date.available2023-09-26T20:44:44Z
dc.identifierARAUJO, Sergio; et al. qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients. PLoS Negl Trop Dis., v.11, n.6, e0005506, 18p, June 2017.
dc.identifier1935-2727
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/24971
dc.identifier10.1371/journal.pntd.0005506
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8863105
dc.descriptionReal-Time PCR-High Resolution Melting (qPCR-HRM) analysis has been recently described for rapid drug susceptibility testing (DST) of Mycobacterium leprae. The purpose of the current study was to further evaluate the validity, reliability, and accuracy of this assay for M. leprae DST in clinical specimens.
dc.formatapplication/pdf
dc.languageeng
dc.publisher1935-2735
dc.rightsopen access
dc.subjectMycobacterium leprae
dc.subjectHanseníase
dc.subjectAnálise em tempo real de PCR
dc.subjecttestes rápidos de susceptibilidade a fármacos
dc.subjectMycobacterium leprae
dc.subjectLeprosy
dc.subjectReal-Time PCR-High Resolution Melting
dc.subjectdrug susceptibility testing
dc.titleqPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients
dc.typeArticle


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