Brasil | Article

Rates of and reasons for failure of commercial human immunodeficiency virus type 1 viral load assays in Brazil

dc.creatorDrexler, Jan Felix
dc.creatorLuna, Luciano Kleber de Souza
dc.creatorPedroso, Celia
dc.creatorSampaio, Diana Brasil Pedral
dc.creatorQueiroz, Artur Trancoso Lopo de
dc.creatorBrites, Carlos
dc.creatorMartins Netto, Eduardo
dc.creatorDrosten, Christian
dc.date2017-06-05T19:07:27Z
dc.date2017-06-05T19:07:27Z
dc.date2007
dc.date.accessioned2023-09-26T20:44:41Z
dc.date.available2023-09-26T20:44:41Z
dc.identifierDREXLER, J. F. et al. Rates of and reasons for failure of commercial human immunodeficiency virus type 1 viral load assays in Brazil. Journal of Clinical Microbiology, v. 45, n. 6, p. 2061–2063, 2007.
dc.identifier0095-1137
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/19303
dc.identifier10.1128/JCM.00136-07
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8863086
dc.descriptionBrazilian Ministry of Health grants CFA 273/04 and CFA 238/05. The Bernhard Nocht Institute receives funding from the German Ministry of Health for operating the National Reference Centre for Tropical Infectious Diseases. L. K. de Souza Luna is receiving a scholarship from the Brazilian National Council of Technological and Scientific Development CNPQ
dc.descriptionWe examined failures of commercial human immunodeficiency virus type 1 (HIV-1) viral load assays of 1,195 plasma samples from Brazilian patients. Assay failure was assumed for samples in which the virus was undetectable by commercial assay but which tested positive by real-time reverse transcription-PCR of the HIV-1 long terminal repeat (LTR) region or if the viral load differed by >2 log10 from that determined by LTR assay. Failure rates for Bayer Versant bDNA 3.0, Roche Amplicor Monitor v1.5, and bioMerieux NucliSens QT were 0.68, 0.47, and 4.33%, respectively. NucliSens may be inadequate for use in Brazil.
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society for Microbiology
dc.rightsopen access
dc.subjectInfecções por HIV
dc.subjectHIV-1
dc.subjectDados de Sequência Molecular
dc.subjectCarga viral
dc.subjectReação em cadeia da polimerase via transcriptase reversa
dc.subjectHumanos
dc.subjectHIV Infections
dc.subjectHIV-1
dc.subjectMolecular Sequence Data
dc.subjectViral Load
dc.subjectReverse Transcriptase Polymerase Chain Reaction
dc.subjectHumans
dc.subjectInfecções por HIV
dc.subjectHIV-1
dc.subjectDados de Sequência Molecular
dc.subjectCarga viral
dc.subjectReação em cadeia da polimerase via transcriptase reversa
dc.subjectHumanos
dc.titleRates of and reasons for failure of commercial human immunodeficiency virus type 1 viral load assays in Brazil
dc.typeArticle


Este ítem pertenece a la siguiente institución