Sexually transmitted infections among HIV serodiscordant partners: A secondary analysis of HIV Prevention Trial Network 052

dc.creatorChagomerana, Maganizo B
dc.creatorHosseinipour, Mina C.
dc.creatorPilotto, Jose Henrique
dc.creatorBadal-Faesen, Sharlaa
dc.creatorNyirenda, Mulinda
dc.creatorShava, Emily
dc.creatorGodbole, Sheela V.
dc.creatorAkelo, Victor
dc.creatorChariyalertsak, Suwat
dc.creatorPanchia, Ravindre
dc.creatorCohen, Myron
dc.date2022-01-10T18:45:29Z
dc.date2022-01-10T18:45:29Z
dc.date2021
dc.date.accessioned2023-09-26T20:43:08Z
dc.date.available2023-09-26T20:43:08Z
dc.identifierCHAGOMERANA, Maganizo B. et al. Sexually transmitted infections among HIV serodiscordant partners: A secondary analysis of HIV Prevention Trial Network 052. International Journal of STD & AIDS, v. 32, n. 13, p. 1204-1211, 2021.
dc.identifier0956-4624
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/50713
dc.identifier10.1177/09564624211030368
dc.identifier1758-1052
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8862600
dc.descriptionSexually transmitted infections (STIs) remain a public health concern because of their interaction(s) with HIV. In the HPTN 052 study, STIs were evaluated in both HIV-positive index cases and their HIV-negative partners at enrollment and at yearly follow-up visits. Our definition for STI was based on any infection with Chlamydia trachomatis, Neisseria gonorrhoeae, syphilis, or Trichomonas vaginalis. We used log-binomial regression models to identify factors associated with prevalent STIs. Generalized estimating equation models with the Poisson distribution were used to compare STI incidence between HIVpositive index cases and HIV-negative partners. 8.1% of the participants had STIs at enrollment. The prevalence of STIs (8.9 vs. 7.2) was higher in HIV-positive index cases than HIV-negative partners. Being female (prevalence ratio (PR) = 1.61; 95% CI: 1.20–2.16) or unmarried (PR = 1.92; 95% CI: 1.17–3.14) was associated with prevalent STIs. Compared to HIV-negative male partners, HIV-positive female index cases had a higher risk of STI acquisition (incidence rate ratio (IRR) = 2.25; 95% CI: 1.70–2.97). While we are implementing HIV prevention interventions for HIV-negative people, we should also intensify targeted STI prevention interventions, especially among HIV-positive women.
dc.formatapplication/pdf
dc.languageeng
dc.publisherSAGE
dc.rightsopen access
dc.subjectTerapia anti-retroviral
dc.subjectHeterossexual
dc.subjectSífilis (Treponema pallidum)
dc.subjectGonorreia (Neisseria gonorrhoeae)
dc.subjectAntiretroviral therapy
dc.subjectHeterosexual
dc.subjectSyphilis (Treponema pallidum)
dc.subjectGonorrhea (Neisseria gonorrhoeae)
dc.subjectChlamydia (Chlamydia trachomatis)
dc.subjectClamídia (Chlamydia trachomatis)
dc.titleSexually transmitted infections among HIV serodiscordant partners: A secondary analysis of HIV Prevention Trial Network 052
dc.typeArticle


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