Clines in clock genes: fine-tuning circadian rhythms to the environment

dc.creatorKyriacou, Charalambos P.
dc.creatorPeixoto, Alexandre A.
dc.creatorSandrelli, Federica
dc.creatorCosta, Rodolfo
dc.creatorTauber, Eran
dc.date2019-02-28T13:40:50Z
dc.date2019-02-28T13:40:50Z
dc.date2008
dc.date.accessioned2023-09-26T20:41:22Z
dc.date.available2023-09-26T20:41:22Z
dc.identifierKYRIACOU, Charalambos P. et al. Clines in clock genes: fine-tuning circadian rhythms to the environment. Trends in Genetics, v.24, n.3, p.124-132, 2007.
dc.identifier0168-9525
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/31921
dc.identifier1362-4555
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8862054
dc.descriptionThe dissection of the circadian clock into its molecular components represents the most striking and well-studied example of a gene regulatory network underlying a complex behavioural trait. By contrast, the evolutionary analysis of the clock has developed more slowly. Here we review studies that have surveyed intraspecific clock gene variation over large geographical areas and have discovered latitudinal clines in gene frequencies. Such spatial patterns traditionally suggest that natural selection shapes genetic variation, but it is equally possible that population history, or a mixture of demography and selection, could contribute to the clines. We discuss how population genetics, together with functional assays, can illuminate these possible cases of natural selection in Drosophila clock genes.
dc.description2022-01-01
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsrestricted access
dc.subjectRelógio circadiano
dc.subjectClines
dc.subjectGenes do relógio
dc.subjectMeio ambiente
dc.subjectGenética populacional
dc.subjectSeleção natural
dc.subjectClock genes
dc.subjectCircadian rhythms
dc.subjectEnvironment
dc.subjectClines
dc.subjectPopulation genetics
dc.subjectNatural selection
dc.titleClines in clock genes: fine-tuning circadian rhythms to the environment
dc.typeArticle


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