Vaccines in leishmaniasis: advances in the last five years

dc.creatorBrodskyn, Claudia Ida
dc.creatorOliveira, Camila Indiani de
dc.creatorBarral, Aldina Maria Prado
dc.creatorBarral Netto, Manoel
dc.date2014-03-21T12:48:03Z
dc.date2014-03-21T12:48:03Z
dc.date2003
dc.date.accessioned2023-09-26T20:40:29Z
dc.date.available2023-09-26T20:40:29Z
dc.identifierBRODSKYN C. et al. Vaccines in leishmaniasis: advances in the last five years. Expert Review of Vaccines, v.2, n.5, p. 705-717, 2003.
dc.identifier1476-0584
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/7433
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8861770
dc.descriptionThe leishmaniases are a group of diseases caused by protozoa of the genus Leishmania which affects millions of people worldwide. The leishmaniases are transmitted to the vertebrate hosts by phlebotomine sand flies. In this review, we focus on clinical aspects of the leishmaniases and on the immune response against the parasite, both in animal models and humans. These aspects are of key importance to understand the many attempts to obtain an effective vaccine against Leishmania. We considered the last advances in new generation vaccines, including the use of new adjuvants to improve the protective response against the parasite. Finally, the possibility to use components of the sand fly saliva as part of vaccines against the infection by Leishmania is mentioned
dc.formatapplication/pdf
dc.languageeng
dc.publisherFuture Drugs LTD
dc.rightsopen access
dc.subjectCo stimulatory molecules
dc.subjectCytokines
dc.subjectImmunoregulation
dc.subjectIVP
dc.subjectLeishmania
dc.subjectLeishmaniasis
dc.subjectSandy fly
dc.subjectVaccine
dc.subjectLeishmaniose Cutânea/prevenção & controle
dc.subjectLeishmaniose Visceral/prevenção & controle
dc.subjectVacinas Protozoárias/imunologia
dc.subjectAnimais
dc.subjectAntiprotozoários/uso terapêutico
dc.subjectHumanos
dc.subjectLeishmania/imunologia
dc.subjectLeishmania/patogenicidade
dc.subjectLeishmaniose Cutânea/quimioterapia
dc.subjectLeishmaniose Cutânea/parasitologia
dc.subjectLeishmaniose Visceral/quimioterapia
dc.subjectLeishmaniose Visceral/parasitologia
dc.subjectVacinas Protozoárias/administração & dosagem
dc.titleVaccines in leishmaniasis: advances in the last five years
dc.typeArticle


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