Distribution of the leptospiral immunoglobulin-like (lig) genes in pathogenic Leptospira species and application of ligB to typing leptospiral isolates.

dc.creatorCerqueira, Gustavo Maia de
dc.creatorMcBride, Alan John Alexander
dc.creatorPicardeau, Mathieu
dc.creatorRibeiro, Samuel G
dc.creatorMoreira, Ângela N
dc.creatorMorel, Viviane
dc.creatorReis, Mitermayer Galvão dos
dc.creatorKo, Albert Icksang
dc.creatorDellagostin, Odir Antonio
dc.date2014-04-14T18:30:01Z
dc.date2014-04-14T18:30:01Z
dc.date2009
dc.date.accessioned2023-09-26T20:40:17Z
dc.date.available2023-09-26T20:40:17Z
dc.identifierCERQUEIRA, G. M. et al. Distribution of the leptospiral immunoglobulin-like (lig) genes in pathogenic Leptospira species and application of ligB to typing leptospiral isolates. Journal of Medical Microbiology, v. 58, n. 9, p. 1173–1181, 2009.
dc.identifier0022-2615
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/7520
dc.identifier10.1099/jmm.0.009175-0
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8861703
dc.descriptionThe family of leptospiral immunoglobulin-like (lig) genes comprises ligA, ligB and ligC. This study used PCR to demonstrate the presence of lig genes among serovars from a collection of leptospiral strains and clinical isolates. Whilst ligA and ligC appeared to be present in a limited number of pathogenic serovars, the ligB gene was distributed ubiquitously among all pathogenic strains. None of the lig genes were detected among intermediate or saprophytic Leptospira species. It was also shown that, similar to the previously characterized secY gene, a short specific PCR fragment of ligB could be used to correctly identify pathogenic Leptospira species. These findings demonstrate that ligB is widely present among pathogenic strains and may be useful for their reliable identification and classification.
dc.formatapplication/pdf
dc.languageeng
dc.publisherSGM
dc.rightsopen access
dc.subjectAntígenos de Bactérias/genética
dc.subjectLeptospira/classificação
dc.subjectLeptospira/genética
dc.subjectAntígenos de Bactérias/química
dc.subjectAntígenos de Bactérias/imunologia
dc.subjectTécnicas de Tipagem Bacteriana
dc.subjectSequência de Bases
dc.subjectDNA Bacteriano/genética
dc.subjectRegulação Bacteriana da Expressão Gênica/fisiologia
dc.subjectLeptospira/imunologia
dc.subjectLeptospira/patogenicidade
dc.subjectDados de Sequência Molecular
dc.subjectFilogenia
dc.subjectRNA Bacteriano/genética
dc.titleDistribution of the leptospiral immunoglobulin-like (lig) genes in pathogenic Leptospira species and application of ligB to typing leptospiral isolates.
dc.typeArticle


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