A systematic scoping review of the genetic ancestry of the Brazilian population

dc.creatorSouza, Aracele Maria de
dc.creatorResende, Sarah Stela
dc.creatorSousa, Taís Nóbrega de
dc.creatorBrito, Cristiana Ferreira Alves de
dc.date2020-02-12T13:33:54Z
dc.date2020-02-12T13:33:54Z
dc.date2019
dc.date.accessioned2023-09-26T20:38:30Z
dc.date.available2023-09-26T20:38:30Z
dc.identifierSOUZA, Aracele Maria de et al. A systematic scoping review of the genetic ancestry of the Brazilian population. Genetics and Molecular Biology, v. 42, n. 3, p. 495-508, 2019.
dc.identifier1415-4757
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/39905
dc.identifier10.1590/1678-4685-gmb-2018-0076
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8861156
dc.descriptionThe genetic background of the Brazilian population is mainly characterized by three parental populations: European, African, and Native American. The aim of this study was to overview the genetic ancestry estimates for different Brazilian geographic regions and analyze factors involved in these estimates. In this systematic scoping review were included 51 studies, comprehending 81 populations of 19 states from five regions of Brazil. To reduce the potential of bias from studies with different sampling methods, we calculated the mean genetic ancestry weighted by the number of individuals. The weighted mean proportions of European, African, and Native American ancestries were 68.1%, 19.6%, and 11.6%, respectively. At the regional level, the highest European contribution occurred in the South, while the highest African and Native American contributions occurred in the Northeastern and Northern regions, respectively. Among states in the Northeast region, Bahia and Ceará showed significant differences, suggesting distinct demographic histories. This review contributes for a broader understanding of the Brazilian ancestry and indicates that the ancestry estimates are influenced by the type of molecular marker and the sampling method.
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedade Brasileira de Genética
dc.rightsopen access
dc.subjectScoping review
dc.subjectGenetic ancestry
dc.subjectBrazilian population
dc.subjectGenetic admixture
dc.titleA systematic scoping review of the genetic ancestry of the Brazilian population
dc.typeArticle


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