Developmental and evolutionary basis for drought tolerance of the Anopheles gambiae embryo

dc.creatorGoltsev, Yury
dc.creatorRezende, Gustavo L.
dc.creatorVranizan, Karen
dc.creatorLanzaro, Greg
dc.creatorValle, Denise
dc.creatorLevine, Michael
dc.date2019-01-15T12:04:27Z
dc.date2019-01-15T12:04:27Z
dc.date2009
dc.date.accessioned2023-09-26T20:38:01Z
dc.date.available2023-09-26T20:38:01Z
dc.identifierGOLTSEV, Yury et al. Developmental and evolutionary basis for drought tolerance of the Anopheles gambiae embryo. Developmental Biology, v. 330, p. 462–470, Mar. 2009.
dc.identifier0012-1606
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/31034
dc.identifier10.1016/j.ydbio.2009.02.038
dc.identifier1095-564X
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8860986
dc.descriptionDuring the evolution of the Diptera there is a dramatic modification of the embryonic ectoderm, whereby mosquitoes contain separate amnion and serosa lineages while higher flies such as Drosophila melanogaster contain a single amnioserosa. Whole-genome transcriptome assays were performed with isolated serosa from Anopheles gambiae embryos. These assays identified a large number of genes implicated in the production of the larval cuticle. In D. melanogaster, these genes are activated just once during embryogenesis, during late stages where they are used for the production of the larval cuticle. Evidence is presented that the serosal cells secrete a dedicated serosal cuticle, which protects A. gambiae embryos from desiccation. Detailed temporal microarray assays of mosquito gene expression profiles revealed that the cuticular genes display biphasic expression during A. gambiae embryogenesis, first in the serosa of early embryos and then again during late stages as seen in D. melanogaster. We discuss how evolutionary modifications in the well-defined dorsal-ventral patterning network led to the wholesale deployment of the cuticle biosynthesis pathway in early embryos of A. gambiae.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsopen access
dc.subjectMosquitos
dc.subjectAnopheles gambiae
dc.subjectMembranas extra-embrionárias
dc.subjectEmbrião
dc.subjectRede reguladora de genes
dc.subjectTolerância à seca
dc.subjectEvolução
dc.subjectMosquito
dc.subjectAnopheles gambiae
dc.subjectEmbryo
dc.subjectExtraembryonic membranes
dc.subjectSerosa
dc.subjectSerosal cuticle
dc.subjectEvolution
dc.subjectMicroarray
dc.subjectGene regulatory network
dc.subjectDrought tolerance
dc.subjectMembrana Serosa
dc.titleDevelopmental and evolutionary basis for drought tolerance of the Anopheles gambiae embryo
dc.typeArticle


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