Splenectomy Improves Hemostatic and Liver Functions in Hepatosplenic Schistosomiasis Mansoni

dc.creatorLeite, Luiz Arthur Calheiros
dc.creatorPimenta Filho, Adenor Almeida
dc.creatorFerreira, Rita de Cássia dos Santos
dc.creatorda Fonseca, Caíque Silveira Martins
dc.creatordos Santos, Bianka Santana
dc.creatorMontenegro, Silvia Maria Lucena
dc.creatorLopes, Edmundo Pessoa de Almeida
dc.creatorDomingues, Ana Lúcia Coutinho
dc.creatorOwen, James Stuart
dc.creatorLima, Vera Lucia de Menezes
dc.date2017-09-21T19:31:35Z
dc.date2017-09-21T19:31:35Z
dc.date2015
dc.date.accessioned2023-09-26T20:37:47Z
dc.date.available2023-09-26T20:37:47Z
dc.identifierLEITE, L. A. C. et al. Splenectomy Improves Hemostatic and Liver Functions in Hepatosplenic Schistosomiasis Mansoni. PloS One, v. 10, n. 8, p. e0135370, 2015.
dc.identifier1932-6203
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/21088
dc.identifier10.1371/journal.pone.0135370
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8860909
dc.descriptionSchistosomiasis mansoni is a chronic liver disease, in which some patients (5-10%) progress to the most severe form, hepatosplenic schistosomiasis. This form is associated with portal hypertension and splenomegaly, and often episodes of gastrointestinal bleeding, even with liver function preserved. Splenectomy is a validated procedure to reduce portal hypertension following digestive bleeding. Here, we evaluate beneficial effects of splenectomy on blood coagulation factors and liver function tests in hepatosplenic schistosomiasis mansoni compared to non-operated patients.
dc.formatapplication/pdf
dc.languagepor
dc.rightsopen access
dc.subjectHemostasia
dc.subjectFígado
dc.subjectEsquistossomose mansoni
dc.subjectEsplenectomia
dc.subjectAlkaline Phosphatase
dc.subjectBilirubin
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectHemostasis
dc.subjectLiver
dc.subjectMiddle Aged
dc.subjectPlasminogen Activator Inhibitor 1
dc.subjectProtein C
dc.subjectProthrombin
dc.subjectSchistosomiasis mansoni
dc.subjectSplenectomy
dc.subjectUltrasonography
dc.subjectHemostasia
dc.subjectFígado
dc.subjectEsquistossomose mansoni
dc.subjectEsplenectomia
dc.subjectHumanos
dc.subjectMasculino
dc.subjectFeminino
dc.subjectFosfatase Alcalina
dc.subjectsangue
dc.subjectBilirrubina
dc.subjectdiagnóstico por imagem
dc.subjectmetabolismo
dc.subjectfisiologia
dc.subjectMeia-Idade
dc.subjectInibidor 1 de Ativador de Plasminogênio
dc.subjectProteína C
dc.subjectProtrombina
dc.titleSplenectomy Improves Hemostatic and Liver Functions in Hepatosplenic Schistosomiasis Mansoni
dc.typeArticle


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