Mediterranean Diet: Lipids, Inflammation, and Malaria Infection

dc.creatorSilva, Adriana R.
dc.creatorMoraes, Bianca P. T.
dc.creatorAlbuquerque, Cassiano F. Gonçalves de
dc.date2020-07-31T19:53:10Z
dc.date2020-07-31T19:53:10Z
dc.date2020
dc.date.accessioned2023-09-26T20:37:38Z
dc.date.available2023-09-26T20:37:38Z
dc.identifierSILVA, Adriana R.; MORAES, Bianca P. T.; ALBUQUERQUE, Cassiano F. Gonçalves de. Mediterranean Diet: Lipids, Inflammation, and Malaria Infection. International Journal of Molecular Science, v. 21, n. 4489, p. 1-22, 2020.
dc.identifier1661-6596
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/42496
dc.identifier10.3390/ijms21124489
dc.identifier1422-0067
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8860860
dc.descriptionThe Mediterranean diet (MedDiet) consists of consumption of vegetables and healthy oils and have beneficial effects on metabolic and inflammatory diseases. Our goal here is to discuss the role of fatty acid content in MedDiet, mostly omega-3, omega-6, and omega-9 on malaria. Malaria affects millions of people around the globe. The parasite Plasmodium causes the disease. The metabolic and inflammatory alterations in the severe forms have damaging consequences to the host. The lipid content in the MedDiet holds anti-inflammatory and pro-resolutive features in the host and have detrimental effects on the Plasmodium. The lipids from the diet impact the balance of pro- and anti-inflammation, thus, lipids intake from the diet is critical to parasite elimination and host tissue damage caused by an immune response. Herein, we go into the cellular and molecular mechanisms and targets of the MedDiet fatty acids in the host and the parasite, reviewing potential benefits of the MedDiet, on inflammation, malaria infection progression, and clinical outcome.
dc.formatapplication/pdf
dc.languageeng
dc.publisherMDPI
dc.rightsopen access
dc.subjectMalária
dc.subjectInflamação
dc.subjectDieta mediterrânea
dc.subjectÁcido graxo
dc.subjectÕmega-3
dc.subjectÕmega-9
dc.subjectÕmega-6
dc.subjectMediterranean diet
dc.subjectFatty acid
dc.subjectOmega-3
dc.subjectOmega-6
dc.subjectOmega-9
dc.subjectInflammation
dc.subjectMalaria
dc.titleMediterranean Diet: Lipids, Inflammation, and Malaria Infection
dc.typeArticle


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