dc.creatorDaliry, Anissa
dc.creatorPereira, Evelyn Nunes Goulart da Silva
dc.date2022-01-24T18:13:20Z
dc.date2022-01-24T18:13:20Z
dc.date2021
dc.date.accessioned2023-09-26T20:37:11Z
dc.date.available2023-09-26T20:37:11Z
dc.identifierDALIRY, Anissa; PEREIRA; Evelyn Nunes Goulart da Silva. Role of Maternal Microbiota and Nutrition in Early-Life Neurodevelopmental Disorders. Nutrients, v. 13, 3533, p. 1 - 21, Oct. 2021.
dc.identifier2072-6643
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/50863
dc.identifier10.3390/nu13103533
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8860701
dc.descriptionThe rise in the prevalence of obesity and other related metabolic diseases has been paralleled by an increase in the frequency of neurodevelopmental problems, which has raised the likelihood of a link between these two phenomena. In this scenario, maternal microbiota is a possible linking mechanistic pathway. According to the “Developmental Origins of Health and Disease” paradigm, environmental exposures (in utero and early life) can permanently alter the body’s structure, physiology, and metabolism, increasing illness risk and/or speeding up disease progression in offspring, adults, and even generations. Nutritional exposure during early developmental stages may induce susceptibility to the later development of human diseases via interactions in the microbiome, including alterations in brain function and behavior of offspring, as explained by the gut–brain axis theory. This review provides an overview of the implications of maternal nutrition on neurodevelopmental disorders and the establishment and maturation of gut microbiota in the offspring.
dc.formatapplication/pdf
dc.languageeng
dc.publisherMDPI
dc.rightsopen access
dc.subjectMicrobiota intestinal
dc.subjectDistúrbios do neurodesenvolvimento
dc.subjectObesidade
dc.subjectEixo intestino-cérebro
dc.subjectDieta materna
dc.subjectGut microbiota
dc.subjectNeurodevelopmental disorders
dc.subjectObesity
dc.subjectGut–brain axis
dc.subjectMaternal diet
dc.titleRole of Maternal Microbiota and Nutrition in Early-Life Neurodevelopmental Disorders
dc.typeArticle


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