Simian malaria in the Brazilian Atlantic forest: first description of natural infection of capuchin monkeys (Cebinae subfamily) by Plasmodium simium.

dc.creatorAlvarenga, Denise Anete Madureira de
dc.creatorCosta, Anielle de Pina
dc.creatorSousa, Taís Nóbrega de
dc.creatorPissinatti, Alcides
dc.creatorZalis, Mariano Gustavo
dc.creatorSuaréz-Mutis, Martha Cecilia
dc.creatorOliveira, Ricardo Lourenço de
dc.creatorBrasil, Patrícia
dc.creatorRibeiro, Cláudio Tadeu Daniel
dc.creatorBrito, Cristiana Ferreira Alves de
dc.date2016-01-28T15:37:11Z
dc.date2016-01-28T15:37:11Z
dc.date2015
dc.date.accessioned2023-09-26T20:36:36Z
dc.date.available2023-09-26T20:36:36Z
dc.identifierALVARENGA, Denise Anete Madureira de et al. Simian malaria in the Brazilian Atlantic forest: first description of natural infection of capuchin monkeys (Cebinae subfamily) by Plasmodium simium. Malaria Journal, vol. 14, n. 1, p. 606, 2015
dc.identifier1475-2875
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/12651
dc.identifier10.1186/s12936-015-0606-6
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8860526
dc.descriptionMethods: Blood samples from 30 non-human primates belonging to nine species kept in the Primate Centre of Rio de Janeiro were collected. Fragments of spleen and liver from one dead monkey found in the neighborhoods of the Primate Centre were also analysed. Molecular diagnosis was performed by nested PCR (18SSU rRNA) and the amplified fragment was sequenced. Results: Thirty per cent of the captive animals were infected with P. simium and/or P. brasilianum. The dead monkey tested positive for DNA of P. simium. For the first time, Cebinae primates (two specimens of genus Cebus and two of genus Sapajos) were found naturally infected by P. simium. The infection was confirmed by sequencing a small fragment of 18SSU rRNA. Conclusion: The results highlight the possibility of infection by P. simium in other species of non-human primates whose impact could be significant for the malaria epidemiology among non-human primates and, if it becomes clear that this P. simium is able to infect monkeys and, eventually, man, also for the maintenance of transmission of human malaria in the context of a zoonosis in areas under influence of the Atlantic Forest.
dc.formatapplication/pdf
dc.languageeng
dc.publisherBioMed Central.
dc.rightsopen access
dc.subjectSimian
dc.subjectmalaria Plasmodium
dc.subjectsimium Plasmodium vivax
dc.subjectPlasmodium brasilianum
dc.subjectPlasmodium malariae Cebinae
dc.subjectMolecular diagnosis
dc.subjectAtlantic Forest
dc.titleSimian malaria in the Brazilian Atlantic forest: first description of natural infection of capuchin monkeys (Cebinae subfamily) by Plasmodium simium.
dc.typeArticle


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