Distinct inflammatory profile underlies pathological increases in creatinine levels associated with Plasmodium vivax malaria clinical severity

dc.creatorCruz, Luís Antonio Bahiana
dc.creatorBarral Netto, Manoel
dc.creatorAndrade, Bruno de Bezerril
dc.date2018-04-18T12:54:31Z
dc.date2018-04-18T12:54:31Z
dc.date2018
dc.date.accessioned2023-09-26T20:34:31Z
dc.date.available2023-09-26T20:34:31Z
dc.identifierCRUZ, L. A. B.; BARRAL NETTO, M.; ANDRADE, B. B. Distinct inflammatory profile underlies pathological increases in creatinine levels associated with Plasmodium vivax malaria clinical severity. PLoS Neglected Tropical Diseases, v. 12, n. 3), e0006306, 2018.
dc.identifierPLoS Neglected Tropical Diseases
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/25925
dc.identifier10.1371/journal.pntd.0006306
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8859837
dc.descriptionFinanciadora de Estudos e Projetos (FINEP) (grant Ward number: 010409605)/ Fundo Nacional de Desenvolvimento Científico e Tecnológico (FNDCT-CT-Amazonia). MB-N is a senior investigator from the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Brazil. LABC received a fellowship from CNPq (154872/2017-2).
dc.descriptionAlthough Plasmodium vivax infection is a frequent cause of malaria worldwide, severe presentations have been more regularly described only in recent years. In this setting, despite clinical descriptions of multi-organ involvement, data associating it with kidney dysfunction are relatively scarce. Here, renal dysfunction is retrospectively analyzed in a large cohort of vivax malaria patients with an attempt to dissect its association with disease severity and mortality, and to determine the role of inflammation in its progression.
dc.formatapplication/pdf
dc.languageeng
dc.publisherPublic Library of Science
dc.rightsopen access
dc.subjectMalária
dc.subjectPlasmodium vivax
dc.subjectCreatinina
dc.subjectMortalidade
dc.subjectHumanos
dc.subjectMalária
dc.subjectPlasmodium vivax
dc.subjectCreatinine
dc.subjectMortality
dc.subjectHumans
dc.titleDistinct inflammatory profile underlies pathological increases in creatinine levels associated with Plasmodium vivax malaria clinical severity
dc.typeArticle


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