Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients

dc.creatorCruz, Rossilene
dc.creatorBührer-Sékula, Samira
dc.creatorPenna, Maria Lucia Fernandes
dc.creatorPenna, Gerson Oliveira
dc.creatorTalhari, Sinésio
dc.date2020-05-11T18:26:12Z
dc.date2020-05-11T18:26:12Z
dc.date2017
dc.date.accessioned2023-09-26T20:33:44Z
dc.date.available2023-09-26T20:33:44Z
dc.identifierCRUZ, Rossilene Conceição da Silva. Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 92, n. 6, p. 761-673, nov./dec. 2017.
dc.identifier1806-4841
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/41186
dc.identifier10.1590/abd1806-4841.20176724
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8859568
dc.descriptionIn this review, the most relevant and current epidemiological data, the main clinical, laboratory and therapeutical aspects of leprosy are presented. Detailed discussion of the main drugs used for leprosy treatment, their most relevant adverse effects, evolution of the therapeutic regimen, from dapsone as a monotherapy to the proposed polychemotherapy by World Health Organization (WHO) can be found in this CME. We specifically highlight the drug acceptability, reduction in treatment duration and the most recent proposal of a single therapeutic regimen, with a fixed six months duration, for all clinical presentations, regardless of their classification.
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedade Brasileira de Dermatologia
dc.rightsopen access
dc.subjectClofazimine
dc.subjectDapsone
dc.subjectDrug Therapy, Combination
dc.subjectLeprostatic Agents
dc.subjectLeprosy
dc.subjectPatient Satisfaction
dc.subjectRifampin
dc.subjectTreatment Outcome
dc.subjectCombined modality therapy
dc.subjectDrug combinations
dc.subjectLeprosy
dc.subjectTherapeutics
dc.subjectClofazimina
dc.subjectDapsona
dc.subjectHansenostáticos
dc.subjectHanseníase
dc.subjectSatisfação do Paciente
dc.subjectRifampina
dc.subjectResultado do Tratamento
dc.titleLeprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients
dc.typeArticle


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