Genome Detective Coronavirus Typing Tool for rapid identification and characterization of novel coronavirus genomes

dc.creatorCleemput, Sara
dc.creatorDumon, Wim
dc.creatorFonseca, Vagner
dc.creatorKarim, Wasim Abdool
dc.creatorGiovanetti, Marta
dc.creatorAlcantara, Luiz Carlos
dc.creatorDeforche, Koen
dc.creatorOliveira, Tulio de
dc.date2020-03-17T13:30:12Z
dc.date2020-03-17T13:30:12Z
dc.date2020
dc.date.accessioned2023-09-26T20:33:19Z
dc.date.available2023-09-26T20:33:19Z
dc.identifierCLEEMPUT, Sara et al. Genome Detective Coronavirus Typing Tool for rapid identification and characterization of novel coronavirus genomes. Bioinformatics, btaa145, p. 1-4, Feb. 2020.
dc.identifier1460-2059
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/40347
dc.identifier10.1093/bioinformatics/btaa145
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8859423
dc.descriptionDevido a pandemia mundial do COVID-19, o artigo da revista foi liberado em acesso aberto durante o ano de 2020, visando divulgação e disseminação.
dc.descriptionEm decorrência da pandemia decretada pela OMS em 2020, o artigo encontra-se em acesso aberto.
dc.descriptionGenome Detective is a web-based, user-friendly software application to quickly and accurately assemble all known virus genomes from next generation sequencing datasets. This application allows the identification of phylogenetic clusters and genotypes from assembled genomes in FASTA format. Since its release in 2019, we have produced a number of typing tools for emergent viruses that have caused large outbreaks, such as Zika and Yellow Fever Virus in Brazil. Here, we present The Genome Detective Coronavirus Typing Tool that can accurately identify the novel severe acute respiratory syndrome (SARS) related coronavirus (SARS-CoV-2) sequences isolated in China and around the world. The tool can accept up to 2,000 sequences per submission and the analysis of a new whole genome sequence will take approximately one minute. The tool has been tested and validated with hundreds of whole genomes from ten coronavirus species, and correctly classified all of the SARS-related coronavirus (SARSr-CoV) and all of the available public data for SARS-CoV-2. The tool also allows tracking of new viral mutations as the outbreak expands globally, which may help to accelerate the development of novel diagnostics, drugs and vaccines to stop the COVID-19 disease.
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dc.formatapplication/vnd.openxmlformats-officedocument.wordprocessingml.document
dc.formatapplication/vnd.openxmlformats-officedocument.wordprocessingml.document
dc.languageeng
dc.publisherOxford University Press
dc.rightsopen access
dc.subjectCoronavírus
dc.subjectTipagem
dc.subjectGenoma
dc.subjectIdentificaçao
dc.subjectCaracterização
dc.subjectFerramenta
dc.subjectCoronavirus Typing Tool
dc.subjectIdentification and characterization
dc.subjectGenomes
dc.subjectCOVID-19
dc.titleGenome Detective Coronavirus Typing Tool for rapid identification and characterization of novel coronavirus genomes
dc.typeArticle


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