dc.creatorFonseca, Erica L.
dc.creatorVieira, Verônica V.
dc.creatorCipriano, Rosângela
dc.creatorVicente, Ana C. P.
dc.date2019-12-12T11:24:08Z
dc.date2019-12-12T11:24:08Z
dc.date2005
dc.date.accessioned2023-09-26T20:32:45Z
dc.date.available2023-09-26T20:32:45Z
dc.identifierFONSECA, Érica L. et al. Class 1 integrons in Pseudomonas aeruginosa isolates from clinical settings in Amazon region, Brazil. FEMS Immunology and Medical Microbiology, v. 44, p. 303-309, 2005.
dc.identifier0928-8244
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/37885
dc.identifier10.1016/j.femsim.2005.01.004
dc.identifier1574-695X
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8859250
dc.descriptionA hundred and six Pseudomonas aeruginosa isolates from clinical cases were screened using PCR for the presence of integrons and associated resistance gene cassettes. Forty-four isolates harboured class 1 integrons (41.5%), of which 29 isolates (66%) also carried gene cassettes. The aacA gene was most frequently found within class 1 integrons (69%), followed by blaOXA family genes (52%). From class 1 integron-positive strains, we detected a total of 15 isolates (34%) carrying no gene cassettes. Restriction fragment-length polymorphism analysis of the integrons variable region revealed some identical structures, as well as distinct profiles indicating heterogeneity among these cassette regions. Multiresistance was observed in 71% of isolates, nevertheless no strong correlation was observed between integron presence and multiresistance. This is the first report showing class 1 integron prevalence and gene cassette content in P. aeruginosa isolates from clinical settings in the Brazilian Amazon.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsrestricted access
dc.subjectPseudomonas aeruginosa
dc.subjectConfiguração clínica da Amazônia
dc.subjectIntegrons Classe 1
dc.subjectClass 1 integron
dc.subjectPseudomonas aeruginosa
dc.subjectAmazon clinical setting
dc.titleClass 1 integrons in Pseudomonas aeruginosa isolates from clinical settings in Amazon region, Brazil
dc.typeArticle


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