Brain schistosomiasis in mice experimentally infected with Schistosoma mansoni

dc.creatorLambertucci, José Roberto
dc.creatorFidelis, Thiago André
dc.creatorPereira, Thiago Almeida
dc.creatorCoelho, Paulo Marcos Zech
dc.creatorPereira, Neusa Araújo
dc.creatorSouza, Márcia Maria de
dc.creatorBrasileiro Filho, Geraldo
dc.creatorPereira, Fausto Edmundo Lima
dc.creatorAntunes, Carlos Mauricio
dc.date2015-02-02T18:30:15Z
dc.date2015-02-02T18:30:15Z
dc.date2014
dc.date.accessioned2023-09-26T20:31:35Z
dc.date.available2023-09-26T20:31:35Z
dc.identifierLAMBERTUCCI, José Roberto et al. Brain schistosomiasis in mice experimentally infected with Schistosoma mansoni. Rev. Soc. Bras. Med. Trop., Uberaba, v. 47, n. 2, 2014 .
dc.identifier0037-8682
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/9412
dc.identifier10.1590/0037-8682-0083-2013
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8858824
dc.descriptionIntroduction: Human neuroschistosomiasis has been reported in the literature, but the possibility of modeling neuroschistosomiasis in mice is controversial. Methods: In two research laboratories in Brazil that maintain the Schistosoma mansoni life cycle in rodents, two mice developed signs of brain disease (hemiplegia and spinning), and both were autopsied. Results: S. mansoni eggs, both with and without granuloma formation, were observed in the brain and meninges of both mice by optical microscopy. Conclusions: This is the first description of eggs in the brains of symptomatic mice that were experimentally infected with S. mansoni. An investigation of experimental neuroschistosomiasis is now feasible.
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedade Brasileira de Medicina Tropical
dc.rightsopen access
dc.subjectSchistosomiasis
dc.subjectExperimental neuroschistosomiasis
dc.subjectBrain schistosomiasis
dc.titleBrain schistosomiasis in mice experimentally infected with Schistosoma mansoni
dc.typeArticle


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