Experimental neuroschistosomiasis: inadequacy of the murine model.

dc.creatorSilva, Luciana Menezes da
dc.creatorOliveira, Carla Neves de
dc.creatorAndrade, Zilton de Araújo
dc.date2012-07-20T18:48:51Z
dc.date2012-07-20T18:48:51Z
dc.date2002
dc.date.accessioned2023-09-26T20:31:04Z
dc.date.available2023-09-26T20:31:04Z
dc.identifierSILVA, L.M.; OLIVEIRA, C.N.; ANDRADE, Z.A. Experimental neuroschistosomiasis: inadequacy of the murine model. Memórias do Instituto Oswaldo Cruz, v. 97, n. 4, p. 599-600, jun. 2002.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/4223
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8858649
dc.descriptionNeuroschistosomiasis is rarely observed in human pathology, but it is of considerable importance. To investigate its pathogenesis, consequences and response to treatment, an experimental model would be desirable, but is not yet available, in spite of a few indications of a suitable mouse model in the literature. Severe, recent and late Schistosoma mansoni infections in outbred and inbred strains of mice revealed widespread distribution of parasite eggs in several organs, but only exceptionally did eggs reach the encephalus, thus revealing the inadequacy of the mouse as an experimental model for neuroschistosomiasis.
dc.formatapplication/pdf
dc.languageeng
dc.rightsopen access
dc.subjectNeuroschistosomiasis
dc.subjectSchistosoma mansoni
dc.subjectMurine model
dc.subjectEncéfalo/parasitologia
dc.subjectModelos Animais de Doenças
dc.subjectNeuroesquistossomose
dc.subjectAnimais
dc.subjectMasculino
dc.subjectFeminino
dc.subjectCamundongos
dc.subjectCamundongos Endogâmicos BALB C
dc.subjectCamundongos Endogâmicos C57BL
dc.subjectContagem de Ovos de Parasitas
dc.titleExperimental neuroschistosomiasis: inadequacy of the murine model.
dc.typeArticle


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