HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil

Teste rápido para o HIV como estratégia de prevenção da transmissão vertical no Brasil

dc.creatorVeloso, Valdiléa G.
dc.creatorBastos, Francisco Inácio Pinkusfeld Monteiro
dc.creatorPortela, Margareth Crisóstomo
dc.creatorGrinsztejn, Beatriz
dc.creatorJoão, Esau Custodio
dc.creatorPilotto, Jose Henrique da Silva
dc.creatorAraújo, Ana Beatriz Busch
dc.creatorSantos, Breno Riegel
dc.creatorFonseca, Rosana Campos da
dc.creatorKreitchmann, Regis
dc.creatorDerrico, Monica
dc.creatorFriedman, Ruth Khalili
dc.creatorMorgado, Mariza Gonçalves
dc.creatorSaines, Karin Nielsen
dc.creatorBryson, Yvonne J.
dc.date2017-02-07T14:18:39Z
dc.date2017-02-07T14:18:39Z
dc.date2010
dc.date.accessioned2023-09-26T20:30:53Z
dc.date.available2023-09-26T20:30:53Z
dc.identifierVeloso, Valdiléa G. et al. HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil. Rev Saúde Pública, v.44, n.5, p.803-11, 2010.
dc.identifier0034-8910
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/17694
dc.identifier1518-8787
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8858573
dc.descriptionOBJECTIVE: To assess the feasibility of HIV rapid testing for pregnant women at maternity hospital admission and of subsequent interventions to reduce perinatal HIV transmission. METHODS: Study based on a convenience sample of women unaware of their HIV serostatus when they were admitted to delivery in public maternity hospitals in Rio de Janeiro and Porto Alegre, Brazil, between March 2000 and April 2002. Women were counseled and tested using the Determine HIV1/2 Rapid Test. HIV infection was confi rmed using the Brazilian algorithm for HIV infection diagnosis. In utero transmission of HIV was determined using HIVDNA- PCR. There were performed descriptive analyses of sociodemographic data, number of previous pregnancies and abortions, number of prenatal care visits, timing of HIV testing, HIV rapid test result, neonatal and mother-tochild transmission interventions, by city studied. RESULTS: HIV prevalence in women was 6.5% (N=1,439) in Porto Alegre and 1.3% (N=3.778) in Rio de Janeiro. In Porto Alegre most of women were tested during labor (88.7%), while in Rio de Janeiro most were tested in the postpartum (67.5%). One hundred and forty-four infants were born to 143 HIVinfected women. All newborns but one in each city received at least prophylaxis with oral zidovudine. It was possible to completely avoid newborn exposure to breast milk in 96.8% and 51.1% of the cases in Porto Alegre and Rio de Janeiro, respectively. Injectable intravenous zidovudine was administered during labor to 68.8% and 27.7% newborns in Porto Alegre and Rio de Janeiro, respectively. Among those from whom blood samples were collected within 48 hours of birth, in utero transmission of HIV was confi rmed in 4 cases in Rio de Janeiro (4/47) and 6 cases in Porto Alegre (6/79). CONCLUSIONS: The strategy proved feasible in maternity hospitals in Rio de Janeiro and Porto Alegre. Efforts must be taken to maximize HIV testing during labor. There is a need of strong social support to provide this population access to health care services after hospital discharge.
dc.formatapplication/pdf
dc.languageeng
dc.publisherUniversidade de São Paulo
dc.rightsopen access
dc.subjectGestantes
dc.subjectCuidados Pré-Natais
dc.subjectSerodiagnóstico
dc.subjectAmamentação
dc.subjectInfecções por HIV
dc.subjectDiagnóstico
dc.subjectTransmissão Vertical de Doenças Infecciosas
dc.subjectSíndrome da Imunodeficiência Adquirida
dc.subjectPrevenção e controle
dc.subjectPregnant Women
dc.subjectPrenatal Care
dc.subjectBreast Feeding
dc.subjectAIDS Serodiagnosis
dc.subjectHIV Infections, diagnosis
dc.subjectInfectious Disease Transmission, Vertical
dc.subjectAcquired Immunodefi ciency Syndrome, prevention & control
dc.titleHIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil
dc.titleTeste rápido para o HIV como estratégia de prevenção da transmissão vertical no Brasil
dc.typeArticle


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