Molecular detection of Leishmania braziliensis in Rattus norvegicus in an area endemic for cutaneous leishmaniasis in Brazil

dc.creatorMarcelino, Andreza Pain
dc.creatorFerreira, Eduardo de Castro
dc.creatorAvendanha, Jerônimo Sérgio
dc.creatorCosta, Cristiano F.
dc.creatorChiarelli, Chiarelli
dc.creatorAlmeida, Gregório
dc.creatorMoreira, Élvio Carlos
dc.creatorLeite, Romulo Cerqueira
dc.creatorGontijo, Célia Maria Ferreira
dc.creatorReis, Jenner Karlisson Pimenta dos
dc.date2014-11-18T11:21:55Z
dc.date2014-11-18T11:21:55Z
dc.date2011
dc.date.accessioned2023-09-26T20:29:59Z
dc.date.available2023-09-26T20:29:59Z
dc.identifierMARCELINO, Andreza Pain et al. Molecular detection of Leishmania braziliensis in Rattus norvegicus in an area endemic for cutaneous leishmaniasis in Brazil. Vet Parasitol, v. 183, n. 1-2, p. 54-58, 2011
dc.identifier0304-4017
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/8882
dc.identifier10.1016/j.vetpar.2011.06.019.
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8858244
dc.descriptionLeishmania nested PCR (LnPCR) targeted to the SSUrRNA gene and DNA sequencing were used to analyze 315 tissue samples from 80 Rattus norvegicus specimens trapped in an area endemic for leishmaniasis in Belo Horizonte, Minas Gerais, Brazil. Of the samples analyzed, 17.46% (55/315) of all tissues, 10% (8/80) of skin, 26.92% (21/78) of blood, 30.76% (24/78) of bone marrow and 2.53% (2/79) of spleen were positive for Leishmania. The overall infection prevalence was 36.25% (29/80) The DNA sequencing showed that 65.51% (19/29) of the positive animals were infected by parasites belonging to theLeishmania braziliensis complex. The identification of L. braziliensis DNA in R. norvegicus in an area with a high prevalence of leishmaniasis might imply a zoonotic role of this species. The rodent control programs and health education may represent important measures toward the control of leishmaniasis.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier Scientific Pub. Co
dc.rightsopen access
dc.subjectRattus norvegicus
dc.subjectLnPCR
dc.subjectSequencing
dc.subjectRodents
dc.subjectLeishmania braziliensis
dc.titleMolecular detection of Leishmania braziliensis in Rattus norvegicus in an area endemic for cutaneous leishmaniasis in Brazil
dc.typeArticle


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