Anti-chikungunya virus seroprevalence in indigenous groups in the São Francisco Valley, Brazil

dc.creatorNicacio, Jandir Mendonça
dc.creatorCunha, Antonio Ricardo Khouri
dc.creatorSilva, Antônio Marconi Leandro da
dc.creatorBarral Netto, Manoel
dc.creatorLima, João Augusto Costa
dc.creatorLadeia, Ana Marice Teixeira
dc.creatorCarmo, Rodrigo Feliciano do
dc.creatorArmstrong, Anderson da Costa
dc.date2021-07-14T18:15:22Z
dc.date2021-07-14T18:15:22Z
dc.date2021
dc.date.accessioned2023-09-26T20:29:36Z
dc.date.available2023-09-26T20:29:36Z
dc.identifierNICACIO, Jandir Mendonça et al. Anti-chikungunya virus seroprevalence in indigenous groups in the São Francisco Valley, Brazil. PLoS Neglected Tropical Diseases, v. 15, n. 6, p. 1-13, 28 June 2021.
dc.identifier1935-2727
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/48239
dc.identifier10.1371/journal.pntd.0009468
dc.identifier1935-2735
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8858114
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico
dc.descriptionFundação Maria Emília
dc.descriptionBackground: Chikungunya fever (CHIKF) is a serious public health problem with a high rate of infection and chronic disabling manifestations that has affected more than 2 million people worldwide since 2005. In spite of this, epidemiological data on vulnerable groups such as Indigenous people are scarce, making it difficult to implement public policies in order to prevent this disease and assist these populations. Objective: To describe the serological and epidemiological profile of chikungunya virus (CHIKV) in two Indigenous populations in Northeast Brazil, as well as in an urbanized control community, and to explore associations between CHIKV and anthropometric variables in these populations. Methodology/Principal findings: This is a cross-sectional ancillary study of the Project of Atherosclerosis among Indigenous Populations (PAI) that included people 30 to 70 years old, recruited from two Indigenous tribes (the less urbanized Fulni-ô and the more urbanized Truká people) and an urbanized non-Indigenous control group from the same area. Subjects underwent clinical evaluation and were tested for anti-CHIKV IgG by enzyme-linked immunosorbent assay. Serological profile was described according to ethnicity, sex, and age. The study population included 433 individuals distributed as follows: 109 (25·2%) Truká, 272 (62·8%) Fulni-ô, and 52 (12%) from the non-Indigenous urbanized control group. Overall prevalence of CHIKV IgG in the study sample was 49.9% (216; 95% CI: 45·1–54·7). When the sample was stratified, positive CHIKV IgG was distributed as follows: no individuals in the Truká group, 78·3% (213/272; 95% CI: 72·9–83·1) in the Fulni-ô group, and 5.8% (3/52; 95% CI: 1.21–16) in the control group. Conclusions/Significance: Positive tests for CHIKV showed a very high prevalence in a traditional Indigenous population, in contrast to the absence of anti-CHIKV serology in the Truká people, who are more urbanized with respect to physical landscape, socio-cultural, and historical aspects, as well as a low prevalence in the non-Indigenous control group, although all groups are located in the same area.
dc.formatapplication/pdf
dc.languageeng
dc.publisherPublic Library of Science
dc.rightsopen access
dc.subjectVírus Chikungunya
dc.subjectFebre de Chikungunya
dc.subjectGrupos populacionais
dc.subjectEstudos soroepidemiológicos
dc.subjectSaúde pública
dc.subjectBrasil
dc.subjectChikungunya virus
dc.subjectChikungunya fever
dc.subjectPopulation groups
dc.subjectSeroepidemiologic studies
dc.subjectPublic health
dc.subjectBrazil
dc.titleAnti-chikungunya virus seroprevalence in indigenous groups in the São Francisco Valley, Brazil
dc.typeArticle


Este ítem pertenece a la siguiente institución