| dc.creator | Figueiredo, Andreza Soriano | |
| dc.creator | Lampe, Elisabeth | |
| dc.creator | Espírito Santo, Márcia Paschoal do | |
| dc.creator | Mello, Francisco Campello do Amaral | |
| dc.creator | Almeida, Fernando Queiroz de | |
| dc.creator | Lemos, Elba Regina Sampaio de | |
| dc.creator | Godoi, Tatianne Leme Oliveira Santos | |
| dc.creator | Dimache, Luana Avila Giorgia | |
| dc.creator | Santos, Debora Regina Lopes dos | |
| dc.creator | Villar, Livia Melo | |
| dc.date | 2016-04-05T16:06:03Z | |
| dc.date | 2016-04-05T16:06:03Z | |
| dc.date | 2015 | |
| dc.date.accessioned | 2023-09-26T20:28:19Z | |
| dc.date.available | 2023-09-26T20:28:19Z | |
| dc.identifier | FIGUEIREDO, Andreza Soriano; et al. Identification of two phylogenetic lineages of equine hepacivirus and high prevalence in Brazil. The Veterinary Journal, v.206, n.3, p.414-416, Dec. 2015. | |
| dc.identifier | 1090-0233 | |
| dc.identifier | https://www.arca.fiocruz.br/handle/icict/13534 | |
| dc.identifier | 10.1016/j.tvjl.2015.10.015 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8857645 | |
| dc.description | Non-primate hepacivirus (NPHV), as described in horses, is the virus most genetically related to hepatitis
C virus (HCV). Although detected worldwide, limited data on genomic variability and distribution
of NPHV are available in Latin America. The aim of this study was to investigate the genetic diversity
and prevalence of equine NPHV in Brazil. Thirteen percent of 202 equines from three Brazilian states were
positive for NPHV genome by reverse transcriptase PCR. Nucleotide sequences of the partial NS5B genome
presented the greatest diversity described to date (25.6%), which is comparable to the upper limit of diversity
for HCV subtype classification for the same region. Phylogenetic analysis revealed that Brazilian
NPHV sequences along with isolates worldwide form two strongly supported clades (pp = 1.0) suggesting
the existence of two distinct lineages. | |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | Elsevier | |
| dc.rights | restricted access | |
| dc.subject | Brazil | |
| dc.subject | Horse | |
| dc.subject | Non-primate hepacivirus | |
| dc.subject | Nucleotide distance | |
| dc.subject | Subtype classification | |
| dc.subject | Hepacivirus | |
| dc.subject | Cavalos | |
| dc.title | Identification of two phylogenetic lineages of equine hepacivirus and high prevalence in Brazil | |
| dc.type | Article | |
