Distribution of human immunodeficiency vrus and human T-leukemia virus co-infection in Bahia, Brazil

dc.creatorPereira, Felicidade Mota
dc.creatorSantos, Fred Luciano Neves
dc.creatorSilva, Ângelo Antônio Oliveira
dc.creatorNascimento, Nathan Menezes
dc.creatorAlmeida, Maria da Conceição Chagas
dc.creatorCarreiro, Roberto Perez
dc.creatorCastro, Bernardo Galvão
dc.creatorGrassi, Maria Fernanda Rios
dc.date2022-03-07T12:57:46Z
dc.date2022-03-07T12:57:46Z
dc.date2022
dc.date.accessioned2023-09-26T20:27:28Z
dc.date.available2023-09-26T20:27:28Z
dc.identifierPereira, Felicidade Mota et.al. Distribution of human immunodeficiency virus and human T-leukemia virus co-infection in Bahia, Brazil. Frontiers in Medicine, v. 8, p. 1-9, 2022.
dc.identifier2296-858X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/51579
dc.identifier10.3389/fmed.2021.788176
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8857340
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq). Fundação Nacional para o Desenvolvimento do Ensino Superior (FUNDADESP). Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB).
dc.descriptionHuman Immunodeficiency Virus (HIV) and Human T-Leukemia Virus (HTLV) are retroviruses that share similar routes of transmission. In Brazil, the prevalence of HIV and HTLV varies according to geographic region. The state of Bahia, located in the Northeast region, is considered endemic for both retroviruses. The present study aimed to characterize the frequency of HIV/HTLV coinfection and evaluate the geographic distribution of coinfection throughout the state. This cross-sectional study was conducted at the state's Central Laboratory of Public Health (LACEN-BA) and included all samples from 2004 to 2013 submitted to serological testing for anti-HIV and anti-HTLV-1/2, screened by chemiluminescence/ELISA and confirmed by Western blot. Infection rates are expressed as the number of infected individuals per 100,000 inhabitants from each municipality. A total of 129,158 samples originating from 358/417 (85.8%) municipalities in Bahia were evaluated. HTLV was detected in 2.4% of the HIV-positive samples (n = 42) compared to 0.5% of those with negative HIV serology (n = 677) (OR: 4.65; CI: 3.39–6.37). HIV/HTLV coinfection was more frequent in women (69.0%); the median age of coinfected individuals was 47.2 years [interquartile range (IQR): 41.6–55.4 years]. In the 14/417 (3.4%) municipalities where at least one case of HIV/HTLV coinfection was detected, the overall HTLV coinfection rate in HIV-positive samples was 0.25 (range: 0.17–13.84) per 100,000 inhabitants. Most cases of HIV/HTLV-1 coinfection (21/37, 57%) were concentrated in the municipality of Salvador. Isolated instances (one or two cases) of HIV/HTLV-1 coinfection were distributed across municipalities known to be endemic for HTLV infection.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFrontiers Media
dc.rightsopen access
dc.subjectHIV
dc.subjectCoinfecção
dc.subjectEpidemiologia
dc.subjectHIV
dc.subjectCoinfection
dc.subjectEpidemiology
dc.subjectVIH
dc.subjectCoinfección
dc.subjectEpidemiología
dc.subjectVIH (Virus de l'Immunodéficience Humaine)
dc.subjectCo-infection
dc.subjectÉpidémiologie
dc.titleDistribution of human immunodeficiency vrus and human T-leukemia virus co-infection in Bahia, Brazil
dc.typeArticle


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