| dc.contributor | Universidade Estadual Paulista (UNESP) | |
| dc.creator | Moraes, R. N. | |
| dc.creator | Macari, Marcos | |
| dc.creator | Pela, I. R. | |
| dc.date | 2014-05-27T00:38:16Z | |
| dc.date | 2016-10-25T18:12:02Z | |
| dc.date | 2014-05-27T00:38:16Z | |
| dc.date | 2016-10-25T18:12:02Z | |
| dc.date | 1985-12-01 | |
| dc.date.accessioned | 2017-04-06T00:40:36Z | |
| dc.date.available | 2017-04-06T00:40:36Z | |
| dc.identifier | Biology of the Neonate, v. 48, n. 5, p. 307-312, 1985. | |
| dc.identifier | 0006-3126 | |
| dc.identifier | http://hdl.handle.net/11449/63733 | |
| dc.identifier | http://acervodigital.unesp.br/handle/11449/63733 | |
| dc.identifier | 10.1159/000242185 | |
| dc.identifier | 2-s2.0-0022377184 | |
| dc.identifier | http://dx.doi.org/10.1159/000242185 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/885708 | |
| dc.description | The febrile response of newborn pigs to exogenous pyrogen injection was investigated. Lipopolysacharides (LPS, E coli) were injected intravenously into the superior vena cava of 1-30-day-old piglets. All the experiments were carried out in littermates half of which were injected with pyrogen and half with pyrogen-free saline. Newborn pigs did not develop a febrile response from 1 to 4 days of age; however, when the animals were 5 days old exogenous pyrogen determined a typical monophasic febrile response. A second intravenous injection of pyrogen into newborn pigs (1 day old) 24 h after the first did not raise body temperature. It is suggested that newborn pigs behave like the newborn of other mammalian species regarding endotoxin-induced thermogenesis. | |
| dc.language | eng | |
| dc.relation | Biology of the Neonate | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | endotoxin | |
| dc.subject | lipopolysaccharide | |
| dc.subject | pyrogen | |
| dc.subject | animal experiment | |
| dc.subject | fever | |
| dc.subject | newborn | |
| dc.subject | nonhuman | |
| dc.subject | priority journal | |
| dc.subject | swine | |
| dc.subject | thermogenesis | |
| dc.subject | Aging | |
| dc.subject | Animal | |
| dc.subject | Animals, Newborn | |
| dc.subject | Escherichia coli | |
| dc.subject | Fever | |
| dc.subject | Kinetics | |
| dc.subject | Lipopolysaccharides | |
| dc.subject | Support, Non-U.S. Gov't | |
| dc.subject | Swine | |
| dc.title | Observations on the development of the febrile response to pyrogen in newborn pigs | |
| dc.type | Otro | |
