Neutralization serotypes of human immunodeficiency virus type 1 field isolates are not predicted by genetic subtype. The WHO network for HIV isolation and characterization.

dc.creatorWeber, Jonathan
dc.creatorFenyo, Eva-Maria
dc.creatorBeddows, Simon
dc.creatorKaleebu, Pontiano
dc.creatorBjorndal, Asa
dc.creatorWho Network for Hiv Isolation and Caracterization. Castro Filho, Bernardo Galvão
dc.date2014-08-20T13:12:06Z
dc.date2014-08-20T13:12:06Z
dc.date1996
dc.date.accessioned2023-09-26T20:26:15Z
dc.date.available2023-09-26T20:26:15Z
dc.identifierWEBER, J. et al. Neutralization serotypes of human immunodeficiency virus type 1 field isolates are not predicted by genetic subtype. The WHO network for HIV isolation and characterization. Journal of Virology, v. 70, n. 11, p. 7827-7832, 1996.
dc.identifier0022-538X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/8211
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8856885
dc.descriptionHuman immunodeficiency virus type 1 (HIV-1) primary isolates from four geographical locations in Thailand, Brazil, Rwanda, and Uganda, representing genetic subtypes A, B, C, D, and E, were examined for autologous and heterologous neutralization by panels of human HIV+ polyclonal plasma. In independent linked experiments in three laboratories using diverse methodologies and common reagents, no defined pattern of genetic subtype-specific neutralization was observed. Most plasma tested were broadly cross-neutralizing across two or more genetic subtypes, although the titer of neutralization varied across a wide range. We conclude that the genetic subtypes of HIV-1 are not classical neutralization serotypes.
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society for Microbiology
dc.rightsopen access
dc.subjectInfecções por HIV/virologia
dc.subjectHIV-1/classificação
dc.subjectHIV-1/imunologia
dc.subjectInfecções por HIV/sangue
dc.subjectInfecções por HIV/imunologia
dc.subjectHumanos
dc.subjectTestes de Neutralização
dc.subjectSorotipagem
dc.titleNeutralization serotypes of human immunodeficiency virus type 1 field isolates are not predicted by genetic subtype. The WHO network for HIV isolation and characterization.
dc.typeArticle


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