On the mechanism of protective action of cold acclimatization against carbon tetrachloride - and ethionine-induced fatty liver

dc.creatorO, Aura Lopez de
dc.creatorG, C. A. Carmona de
dc.creatorMoussatche, H.
dc.date2020-09-23T19:20:54Z
dc.date2020-09-23T19:20:54Z
dc.date1993
dc.date.accessioned2023-09-26T20:25:56Z
dc.date.available2023-09-26T20:25:56Z
dc.identifierO, Aura Looez de; G., C. A. Carmona; MOUSSATCHE, H. On the mechanism of protective action of cold acclimatization against carbon tetrachloride - and ethionine-induced fatty liver. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 88, n. 2, p. 313-316, Apr./June 1993.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/43585
dc.identifier10.1590/S0074-02761993000200023
dc.identifier1678-8060
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8856764
dc.descriptionIn this study the hepatic lipoprotein lipase (LPL), activity was evaluated in adult female mice acclimatized at 5-C and submitted to carbon tetrachloride (CCI) or ethionine, in order to determine the possible role of this enzuyme in the fatty liver. The results were compared with those obtained in mice kept at room temperature (27-C) that the same hepatoesteatosis inducing agent. In contrast to animals kept at room temperature, in cold aclimatized mice neither the enhancement of the LPL-liver activity by the action of CCI or ethionine occurred nor the development of fatty infiltration in the liver was observed. We conclude that the low temperature induced a protective effect against CCI or ethionine-induced fatty liver that was correlated with the no-increase of the hepatic LPL activity.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.rightsopen access
dc.subjectLipoproteína lipase hepática
dc.subjectFígado gordo
dc.subjectTetracloreto de carbono
dc.subjectEtionina
dc.subjectHepatic lipoprotein lipase
dc.subjectFatty liver
dc.subjectCarbon tetrachloride
dc.subjectEthionine
dc.titleOn the mechanism of protective action of cold acclimatization against carbon tetrachloride - and ethionine-induced fatty liver
dc.typeArticle


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