Estudo sorbre o papel dos eosinófilos na destruicão dos esquistossômulos do Schistosoma mansoni in vivo

dc.creatorAndrade, Zilton de Araújo
dc.creatorReis, Mitermayer Galvão dos
dc.date2014-05-06T13:01:46Z
dc.date2014-05-06T13:01:46Z
dc.date1984
dc.date.accessioned2023-09-26T20:22:48Z
dc.date.available2023-09-26T20:22:48Z
dc.identifierANDRADE, Z. A.; REIS, M. G. dos Estudo sorbre o papel dos eosinófilos na destruicão dos esquistossômulos do Schistosoma mansoni in vivo. Memórias do Instituto Oswaldo Cruz, v. 79, n. 3, p. 371-373, 1984.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/7583
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8855590
dc.descriptionSchistosoma mansoni cercariae mechanically transformed into schistosomula were injected, either dead or alive, into the tail vein (2.000 larvae/0,15 ml) of Balb/c mice which were either previously infected with S. mansoni (10 weeks/50 cercariae) or non-infected. Histological examination of the lungs 24, 48, 72 and 96 hours after injection revealed that inflammatory reaction around schistosomula occurred only in the groups injected with dead schistosomula (killed by freezing and thawing). In non-infected animals the reaction was predominantly macrophagic while in those infected many eosinophils appeared around the dead larvae. These results are at variance with those obtained in vitro and suggest that in vivo the participation of eosinophils in the schistosomulum induced reaction in sensitized animals is secondary to the death of the larvae
dc.formatapplication/pdf
dc.languagepor
dc.publisherFiocruz
dc.rightsopen access
dc.subjectAnticorpos/imunologia
dc.subjectEosinófilos/fisiologia
dc.subjectSchistosoma mansoni/imunologia
dc.subjectAnimais
dc.subjectFormação de Anticorpos
dc.subjectInterações Hospedeiro-Parasita
dc.subjectPulmão/patologia
dc.subjectCamundongos
dc.subjectCamundongos Endogâmicos BALB C
dc.subjectEsquistossomose/imunologia
dc.subjectEsquistossomose/patologia
dc.titleEstudo sorbre o papel dos eosinófilos na destruicão dos esquistossômulos do Schistosoma mansoni in vivo
dc.typeArticle


Este ítem pertenece a la siguiente institución