Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism

dc.creatorGazzinelli, Ricardo Tostes
dc.creatorDenkers, Eric Y.
dc.date2013-10-15T12:35:28Z
dc.date2013-10-15T12:35:28Z
dc.date2006
dc.date.accessioned2023-09-26T20:19:20Z
dc.date.available2023-09-26T20:19:20Z
dc.identifierGAZZINELLI, Ricardo Tostes; DENKERS, Eric Y. Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism. Nat Rev Immunol. 2006;6(12):895-906
dc.identifier1474-1733
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/7143
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8854186
dc.descriptionToll-like receptors (TLRs) have emerged as a major receptor family involved in non-self recognition. They have a vital role in triggering innate immunity and orchestrate the acquired immune response during bacterial and viral infection. However, the role of TLRs during infection with protozoan pathogens is less clear. Nevertheless, our understanding of how these parasitic microorganisms engage the host TLR signalling system has now entered a phase of rapid expansion. This Review describes recent insights into how parasitic protozoans are sensed by TLR molecules, and how the TLR system itself can be targeted by these microbial pathogens for their own survival
dc.formatapplication/pdf
dc.languageeng
dc.publisherNature Pub. Group
dc.rightsrestricted access
dc.subjectEukaryota/immunology
dc.subjectHost-Parasite Interactions
dc.subjectProtozoan Infections/immunology
dc.subjectSignal Transduction
dc.subjectToll-Like Receptors/physiology
dc.titleProtozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism
dc.typeArticle


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