High frequency of M. leprae DNA detection in asymptomatic household contacts

dc.creatorGama, Rafael Silva
dc.creatorGomides, Thalisson Artur Ribeiro
dc.creatorGama, Chaiana Fróes Magalhães
dc.creatorMoreira, Suelen Justo Maria
dc.creatorManta, Fernanda Saloum de Neves
dc.creatorOliveira, Lorena Bruna P. de
dc.creatorMarçal, Pedro Henrique Ferreira
dc.creatorSarno, Euzenir Nunes
dc.creatorMoraes, Milton Ozório
dc.creatorGarcia, Raúl Marcel González
dc.creatorFraga, Lucia Alves de Oliveira
dc.date2018-09-28T14:38:42Z
dc.date2018-09-28T14:38:42Z
dc.date2018
dc.date.accessioned2023-09-26T20:19:17Z
dc.date.available2023-09-26T20:19:17Z
dc.identifierGAMA, Rafael Silva; et al. High frequency of M. leprae DNA detection in asymptomatic household contacts. BMC Infectious Diseases, v.18, n.153, 6p, 2018.
dc.identifier1471-2334
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/29150
dc.identifier10.1186/s12879-018-3056-2
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8854167
dc.descriptionCharacterization of the Mycobacterium leprae genome has made possible the development of Polymerase Chain Reaction (PCR) systems that can amplify different genomic regions. Increased reliability and technical efficiency of quantitative PCR (qPCR) makes it a promising tool for early diagnosis of leprosy. Index cases that are multibacillary spread the bacillus silently, even before they are clinically diagnosed. Early detection and treatment could prevent transmission in endemic areas.
dc.formatapplication/pdf
dc.languageeng
dc.publisherBioMed Central
dc.rightsopen access
dc.subjectHanseníase
dc.subjectContatos do agregado familiar
dc.subjectReação em Cadeia da Polimerase
dc.subjectLeprosy
dc.subjectHousehold contacts
dc.subjectqPCR
dc.titleHigh frequency of M. leprae DNA detection in asymptomatic household contacts
dc.typeArticle


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