Parasite Genotypically Related to a Monoxenous Trypanosomatid of Dog`s Flea Causing Opportunistic Infection in an HIV Positive Patient

dc.creatorPacheco, Raquel S.
dc.creatorMarzochi, Mauro C. A.
dc.creatorPires, Marize Q.
dc.creatorBrito, Célia M. M .
dc.creatorMadeira, Maria de Fátima
dc.creatorSantos, Elizabeth G. O. Barbosa
dc.date2020-10-12T16:45:46Z
dc.date2020-10-12T16:45:46Z
dc.date1998
dc.date.accessioned2023-09-26T20:17:53Z
dc.date.available2023-09-26T20:17:53Z
dc.identifierPACHECO, Raquel S. et al. Parasite Genotypically Related to a Monoxenous Trypanosomatid of Dog s Flea Causing Opportunistic Infection in an HIV Positive Patient. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 93, n. 4, p. 531-537, July/Aug. 1998.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/43938
dc.identifier10.1590/S0074-02761998000400021
dc.identifier1678-8060
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8853618
dc.descriptionAn HIV positive patient presenting a clinical picture of visceral leishmaniasis co-infection was submitted to a bone marrow aspiration after admission to hospital. Amastigotes forms were seen in the bone marrow aspirate and the parasite grew in culture as promastigotes. Molecular analyses showed that the flagellates isolated did not belong to the genera Leishmania, Trypanosoma or Sauroleishmania. It was not possible to establish infection in laboratory animals. In vitro culture of mouse peritoneal macrophages revealed the invasion of the host cells by the flagellates and their killing 48 hr after infection. Opportunistic infection with an insect trypanosomatid was suspected. Further hybridization analyses against a pannel of different monoxenous and heteroxenous trypanosomatids showed kDNA cross-homology with Leptomonas pulexsimulantis a trypanosomatid found in the dog’s flea.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.rightsrestricted access
dc.subjectAIDS
dc.subjectInfecção oportunista
dc.subjectTrippanosomatidio monoxenous
dc.subjectHibridação
dc.subjectMinicirculo
dc.subjectOpportunistic infection
dc.subjectAIDS
dc.subjectMonoxenous trypanosomatid
dc.subjectMinicircle
dc.subjectHybridization
dc.titleParasite Genotypically Related to a Monoxenous Trypanosomatid of Dog`s Flea Causing Opportunistic Infection in an HIV Positive Patient
dc.typeArticle


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