Diagnostic and therapeutic biomarkers in colorectal cancer: a review

dc.creatorAssis, Jéssica Vieira de
dc.creatorCoutinho, Lucélia Antunes
dc.creatorOyeyemi, Ifeoluwa Temitayo
dc.creatorOyeyemi, Oyetunde Timothy
dc.creatorQueiroz, Rafaella Fortini Grenfell e
dc.date2022-12-20T12:18:42Z
dc.date2022-12-20T12:18:42Z
dc.date2022
dc.date.accessioned2023-09-26T20:17:03Z
dc.date.available2023-09-26T20:17:03Z
dc.identifierASSIS, Jéssica Vieira de et al. Diagnostic and therapeutic biomarkers in colorectal cancer: a review. Am J Cancer Res., v. 12, n. 2, p. 661-680.
dc.identifier2156-6976
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/56077
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8853291
dc.descriptionColorectal cancer (CRC) is a public health concern and the second most common type of cancer among men and women causing a significant mortality. Biomarkers closely linked to the disease morbidity could holds potential as diagnostic and/or prognostic biomarker for the disease. This review provides an overview of recent advances in the search for colorectal cancer biomarkers through genomics and proteomics according to clinical function and application. Specifically, a number of biomarkers were identified and discussed. Emphasis was placed on their clinical applications relative to the diagnosis and prognosis of CRC. The discovery of more sensitive and specific markers for CRC is an urgent need, and the study of molecular targets is extremely important in this process, as they will allow for a better understanding of colorectal carcinogenesis, identification and validation of potential genetic signatures.
dc.formatapplication/pdf
dc.languageeng
dc.publishere-Century Pub. Corp.
dc.rightsopen access
dc.subjectBiomarkers
dc.subjectcolorectal cancer
dc.subjectmanagement
dc.subjectprognosis
dc.titleDiagnostic and therapeutic biomarkers in colorectal cancer: a review
dc.typeArticle


Este ítem pertenece a la siguiente institución