Lung Atelectasis Promotes Immune and Barrier Dysfunction as Revealed by Transcriptome Sequencing in Female Sheep

dc.creatorZeng, Congli
dc.creatorRibeiro, Gabriel C. Motta
dc.creatorHinoshita, Takuga
dc.creatorLessa, Marcos Adriano
dc.creatorWinkler, Tilo
dc.creatorGorgg, Kira
dc.creatorKingston, Nathan M.
dc.creatorHutchinson, John N.
dc.creatorSholl, Lynette Marie
dc.creatorFang, Xiangming
dc.creatorVarelas, Xaralabos
dc.creatorLayne, Matthew D.
dc.creatorBaron, Rebecca M.
dc.creatorMelo, Marcos F. Vidal
dc.date2021-07-19T17:55:04Z
dc.date2021-07-19T17:55:04Z
dc.date2020
dc.date.accessioned2023-09-26T20:13:37Z
dc.date.available2023-09-26T20:13:37Z
dc.identifierZENG, Congli et al. Lung Atelectasis Promotes Immune and Barrier Dysfunction as Revealed by Transcriptome Sequencing in Female Sheep. Anesthesiology, v. 133, n. 5, 17 p, Nov. 2020.
dc.identifier1528-1175
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/48282
dc.identifier10.1097/ALN.0000000000003491
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8851877
dc.descriptionPulmonary atelectasis is frequent in clinical settings. Yet there is limited mechanistic understanding and substantial clinical and biologic contro versy on its consequences. The authors hypothesize that atelectasis produces local transcriptomic changes related to immunity and alveolar–capillary barrier function conducive to lung injury and further exacerbated by systemic inflammation.
dc.description2023
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society of Anesthesiologists
dc.rightsrestricted access
dc.subjectAtelectasia pulmonar
dc.subjectPromove Imune e barreira disfunção
dc.subjectSeqüenciamento de transcriptoma
dc.subjectOvelhas
dc.subjectLung Atelectasis
dc.subjectPromote Barrier Dysfunction
dc.subjectPromote Imune Dysfunction
dc.subjectFemale Sheep
dc.subjectTranscriptome Sequencing
dc.titleLung Atelectasis Promotes Immune and Barrier Dysfunction as Revealed by Transcriptome Sequencing in Female Sheep
dc.typeArticle


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