Glutathione and metallothionein as oxidative stress biomarkers in the medicinal plant Chrysobalanus icaco L. from different Brazilian regions

dc.creatorPedrete, Thaís A.
dc.creatorHauser-Davis, Rachel A.
dc.creatorPereira, Lucia H. S. S.
dc.creatorTorres, Mylena B.
dc.creatorMoreira, Josino C,
dc.date2020-08-27T13:51:00Z
dc.date2020-08-27T13:51:00Z
dc.date2020
dc.date.accessioned2023-09-26T20:12:46Z
dc.date.available2023-09-26T20:12:46Z
dc.identifierPEDRETE, Thaís A. et al. Glutathione and metallothionein as oxidative stress biomarkers in the medicinal plant Chrysobalanus icaco L. from different Brazilian regions. Journal of Plant Biology and Crop Research, v. 3, n. 1, p. 1-6, Mar. 2020.
dc.identifier2637-7721
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/43029
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8851518
dc.descriptionAbiotic stresses usually result in the overproduction of Reactive Oxygen Species (ROS), which cause oxidative damage. ROS regulation is vital to improve plant resistance to stress and is implemented by a defense system. Higher levels of glutathione (GSH) and Metallothionein (MT) indicate a defense mechanism in response to oxidative stress, participating in ROS detoxification. The abajerú (Chrysobalanus icaco L.) leaf extract is used in folk medicine to control glucose levels in diabetic individuals. This effect may be altered due to abiotic factors that differ according to the region where C. icaco occurs, reflected in oxidative stress biomarker levels. In this context, the aim of this study was to evaluate and compare GSH and MT levels in C. icaco specimens from different Brazilian regions. A statistically significant difference in GSH and MT levels was observed between Southeastern and Northeastern samples, indicating that regionalization may interfere in the biochemistry of C. icaco leaf extracts. Furthermore, a statistically significant correlation between GSH and MT levels was noted, which may be linked to metal exposure, which induces MT expression which then acts against ROS, and corroborates that GSH expression may also be related to metal contamination.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsopen access
dc.subjectGlutationa
dc.subjectMetalotioneína
dc.subjectEstresse oxidativo
dc.subjectHipoglicemiante
dc.subjectChrysobalanus icaco
dc.subjectRegionalização
dc.subjectGlutathione
dc.subjectMetallothionein
dc.subjectOxidative stress
dc.subjectHypoglycemiant
dc.subjectChrysobalanus icaco
dc.subjectRegionalization
dc.titleGlutathione and metallothionein as oxidative stress biomarkers in the medicinal plant Chrysobalanus icaco L. from different Brazilian regions
dc.typeArticle


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