Congenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases

dc.creatorDias, Eliane Pedra
dc.creatorBarcelos, Jose Maria Pinto
dc.creatorFonseca, Evangelina Ferreira
dc.creatorBasso, Nádia Gomes da Silva
dc.date2019-10-21T16:55:10Z
dc.date2019-10-21T16:55:10Z
dc.date1995
dc.date.accessioned2023-09-26T20:12:29Z
dc.date.available2023-09-26T20:12:29Z
dc.identifierDIAS, Eliane Pedra et al. Congenital papillomas and papillomatoses associated with the Human Papilloma Virus (HPV): report on 5 cases. São Paulo Medical Journal, v. 113, n. 4, p. 957-963, 1995.
dc.identifier1516-3180
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/36609
dc.identifier10.1590/s1516-31801995000400007
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8851387
dc.descriptionIntrodução: Os autores apresentam um estudo de cinco casos de papilomas e papilomatoses vulvares congênitas em neo e nati-mortos. Material e Métodos: O material utilizado foi proveniente de cinco necrópsias. A avaliação histopatológica mostrou aspectos sugestivos de infecção pelo Pailomavirus humano (HPV). A microscopia eletrônica de três dos casos identificou partículas viróticas nucleares e citoplasmáticas variando de 40 a 60 nm, compatíveis com HPV. Resultados: O estudo imunohistoquímico destas lesões demonstrou imunopositividade citoplasmática e nuclear. Conclusão: Os autores concluíram que a presença de partículas viróticas somada a imunopositividade em células escamosas, são evidências do provável envolvimento etiológico do HPV nestas lesões.
dc.descriptionThe authors present a study of five cases of vulvar congenital papillomas and papillomatoses in stillborns and neonates dead upon birth. The studied material was collected from five necropsies. The histopathological evaluation showed hyperkeratosis, acanthosis, papillomatosis, perinuclear haloes, and nuclear abnormalities. In three of the cases, the electron microscopy identified nuclear and cytoplasmatic viral particles ranging from 40 to 60 nm in size, compatible with HPV. The immunohistochemical study of those lesions showed nuclear and cytoplasmatic positivity. The authors concluded that the presence of viral particles suggestive of HPV added to the immunopositivity indicated the possibility of viral infection.
dc.formatapplication/pdf
dc.languageeng
dc.publisherAssociação Paulista de Medicina
dc.rightsopen access
dc.subjectPapillomavirus Infections
dc.subjectPregnancy Complications, Infectious
dc.subjectTumor Virus Infections
dc.subjectVulvar Diseases
dc.subjectInfant Newborn
dc.subjectPregnancy
dc.subjectFemale
dc.subjectHumans
dc.subjectCongenital Papilloma
dc.subjectHPV
dc.subjectPapillomatosis
dc.titleCongenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases
dc.typeArticle


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