Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy

dc.creatorLeite, A. C. C. B.
dc.creatorSilva, M. T. T.
dc.creatorAlamy, A. H.
dc.creatorAfonso, C. R.
dc.creatorLima, M. A.
dc.creatorSerpa, M. J. A.
dc.creatorNascimento, O. J.
dc.creatorAraújo, A. Q. C.
dc.date2019-05-08T13:03:43Z
dc.date2019-05-08T13:03:43Z
dc.date2004
dc.date.accessioned2023-09-26T20:12:01Z
dc.date.available2023-09-26T20:12:01Z
dc.identifierLEITE, Ana C. C. L. et al. Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy. Journal of Neurology, v. 251, n. 7, p. 877-881, July 2004.
dc.identifier0340-5354
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/32991
dc.identifier10.1007/s00415-004-0455-7
dc.identifier1432-1459
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8851167
dc.descriptionTropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM) is the classical neurological manifestation of HTLV-I. Only a few studies have described isolated peripheral neuropathy (PN) among HTLV-I infected individuals. 335 infected individuals without TSP/HAM were evaluated for the presence of PN and 45 of them showed evidences of peripheral nervous system involvement. Of these 21 patients had isolated PN, defined by clinical and/or electrophysiological criteria. Sural nerve biopsies revealed inflammatory infiltrates in 2, axonal degeneration in 2 and segmental demyelination in 1. Therefore, peripheral neuropathy can be found as an isolated manifestation of HTLV-I infection. We conclude that HTLV-I infection should be investigated in patients with PN of unknown origin.
dc.description2020-05-08
dc.formatapplication/pdf
dc.languageeng
dc.publisherSpringer Verlag
dc.rightsopen access
dc.subjectHTLV-I
dc.subjectPeripheral neuropathy
dc.subjectTSP/HAM
dc.titlePeripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy
dc.typeArticle


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