First Detection of the CTXM-15 Producing Escherichia coli O25-ST131 Pandemic Clone in Ecuador

dc.creatorChiluisa-Guacho, Carlos
dc.creatorEscobar-Perez, Javier
dc.creatorAsensi, Marise Dutra
dc.date2020-04-28T18:28:08Z
dc.date2020-04-28T18:28:08Z
dc.date2018
dc.date.accessioned2023-09-26T20:12:00Z
dc.date.available2023-09-26T20:12:00Z
dc.identifierCHILUISA-GUACHO, Carlos; ESCOBAR-PEREZ, Javier; ASENSI, Marise Dutra. First Detection of the CTXM-15 Producing Escherichia coli O25-ST131 Pandemic Clone in Ecuador. Pathogens, v. 7, n. 42, 4p, 2018.
dc.identifier2076-0817
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/41019
dc.identifier10.3390/pathogens7020042
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8851161
dc.descriptionOur aim was identify of the pandemic B2-ST131 Escherichia coli clone by to the Institute Pasteur and Achtman scheme, and investigate the resistance profile phenotypic-genotypic, with identification of class 1 integron. Of thirty-five ESBL-producing isolates recovered of patients with diagnosis of urinary tract infections (UTI), six E. coli strains serotype O25 were identified with resistance antimicrobial to several groups of antibiotics such as broad-spectrum cephalosporins, fluoroquinolones and aminoglycosides, harboring blaSHV, blaCTX-M genes in all isolates and blaTEM in two isolates. Sequencing of blaCTX-M revealed CTX-M-15 in all strains. The PMQR aac(6’)-Ib-cr and qnrB19 genes were presented in five and four isolates respectively, AMEs genes aac(6’)-Ib and aac(3)-IIa were presented in strain amikacin-gentamicin-resistant. Sequencing of the variable regions of the class 1 integron revealed dfrA and aadA genes cassette. The analysis of multilocus sequence typing (MLST) confirms the presence of the pandemic B2-ST131 E. coli clone by Achtman scheme in all ST43 isolates obtained by of the Institute Pasteur scheme. The results presented herein, reveal the presence of B2-ST131 E. coli clone in Ecuador, disseminated in hospitals and community settings.
dc.formatapplication/pdf
dc.languageeng
dc.publisherMDPI
dc.rightsopen access
dc.subjectEscherichia coli
dc.subjectST131
dc.subjectESBL
dc.subjectMLST
dc.subjectResistência
dc.subjectEscherichia coli
dc.subjectST131
dc.subjectESBL
dc.subjectMLST
dc.subjectResistance
dc.titleFirst Detection of the CTXM-15 Producing Escherichia coli O25-ST131 Pandemic Clone in Ecuador
dc.typeArticle


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