Schistosoma mansoni infection and nutritional status in schoolchildren: a randomized, double-blind trial in northeastern Brazil

dc.creatorOliveira, Ana Marlucia de
dc.creatorBarreto, Maurício Lima
dc.creatorPrado, Matildes da Silva
dc.creatorReis, Mitermayer Galvão dos
dc.creatorParraga, Isabel Martin
dc.creatorBlanton, Ronald Edward
dc.date2014-05-05T12:50:12Z
dc.date2014-05-05T12:50:12Z
dc.date1998
dc.date.accessioned2023-09-26T20:11:16Z
dc.date.available2023-09-26T20:11:16Z
dc.identifierASSIS, A. M. O. et al. Schistosoma mansoni infection and nutritional status in schoolchildren: a randomized, double-blind trial in northeastern Brazil. American Journal of Clinical Nutrition, v. 68, n. 6, p. 1247-1253, 1998.
dc.identifier0002-9165
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/7575
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8850805
dc.descriptionBrazilian schoolchildren with mild- to moderate-intensity schistosome infections (<400 Schistosoma mansoni eggs/g stool) were randomly allocated to a treatment (oxamniquine) or placebo group in a double-blind fashion. Anthropometric measurements were made at baseline, 6 mo, and 1 y for 353 students. At baseline, the groups were not significantly different with respect to nutritional status or selected socioeconomic and biological characteristics, including anthropometric measures. One year later, significant differences were noted only in the nutritional status of boys treated for schistosome infection. Treated boys had greater measurements for weight, triceps skinfold thickness, midarm circumference, arm muscle area, and body mass index than untreated boys. They also showed significant increases over the year in weight, height, midarm circumference, and body mass index. The rates of improvement in weight and height were more accelerated in the first 6 mo after therapy than the last. These results indicate that, at least in boys, chronic S. mansoni infection at any intensity is detrimental to short-term growth and development.
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society for Clinical Nutrition
dc.rightsrestricted access
dc.subjectSchistosoma mansoni
dc.subjectGrowth
dc.subjectSex
dc.subjectOxamniquine
dc.subjectMorbidity
dc.subjectTherapy
dc.subjectAnthropometry
dc.subjectParasitic infection
dc.subjectSchoolchildren
dc.subjectEstado Nutricional
dc.subjectOxamniquine/uso terapêutico
dc.subjectEsquistossomose mansoni/quimioterapia
dc.subjectEsquistossomicidas/uso terapêutico
dc.subjectAdolescente
dc.subjectAntropometria
dc.subjectÍndice de Massa Corporal
dc.subjectPeso Corporal
dc.subjectBrasil
dc.subjectCriança
dc.subjectMétodo Duplo-Cego
dc.subjectFeminino
dc.subjectHumanos
dc.subjectMasculino
dc.subjectPlacebos
dc.subjectEsquistossomose mansoni/fisiopatologia
dc.subjectPregas Cutâneas
dc.titleSchistosoma mansoni infection and nutritional status in schoolchildren: a randomized, double-blind trial in northeastern Brazil
dc.typeArticle


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