Enterovirus infection and its relationship with neurodegenerative diseases

dc.creatorSousa Junior, Ivanildo Pedro
dc.creatorVieira, Tuane Cristine Ramos Gonçalves
dc.date2023-02-11T13:37:15Z
dc.date2023-02-11T13:37:15Z
dc.date2023
dc.date.accessioned2023-09-26T20:08:44Z
dc.date.available2023-09-26T20:08:44Z
dc.identifierSOUSA JUNIOR, Ivanildo Pedro; VIEIRA, Tuane Cristine Ramos Gonçalves. Enterovirus infection and its relationship with neurodegenerative diseases. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 118, e220252, p. 1-7, 2023.
dc.identifier0074-0206
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/57021
dc.identifier10.1590/0074-02760220252
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8849638
dc.descriptionNeurodegenerative diseases (NDs) are increasingly common, especially in populations with higher life expectancies. They are associated mainly with protein metabolism and structure changes, leading to neuronal cell death. Viral infections affect these cellular processes and may be involved in the etiology of several neurological illnesses, particularly NDs. Enteroviruses (EVs) frequently infect the central nervous system (CNS), causing neurological disease. Inflammation, disruption of the host autophagy machinery, and deregulation and accumulation/misfolding of proteins are the main alterations observed after infection by an EV. In this perspective, we discuss the most recent findings on the subject, examining the possible role of EVs in the development of NDs, and shedding light on the putative role played by these viruses in developing NDs.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFiocruz/IOC
dc.rightsopen access
dc.subjectEnterovirus
dc.subjectDoenças neurodegenerativas
dc.subjectEsclerose Lateral Amiotrófica
dc.subjectMal de Parkinson
dc.subjectDoença de Alzheimer
dc.subjectEnterovirus
dc.subjectNeurodegenerative diseases
dc.subjectAmyotrophic lateral sclerosis
dc.subjectParkinson’s disease
dc.subjectAlzheimer’s disease
dc.titleEnterovirus infection and its relationship with neurodegenerative diseases
dc.typeArticle


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